Patents by Inventor Ashwini Kumar Banala

Ashwini Kumar Banala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-Aza-2, 3-didehydropodophyllotoxin compounds and process for the preparation thereof
    Patent number: 8927560
    Abstract: The present invention provides 4-Aza-2,3-didehydropodophyllotoxin compound of general formula A (4a-4z and 4aa-4ae) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis of 4-Aza-2,3-didehydropodophyllotoxin compounds (4a-4z and 4aa-4ae).
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: January 6, 2015
    Assignee: Council of Scientific & Industrial Research
    Inventors: Kamal Ahmed, Suresh Paidakula, Ashwini Kumar Banala, Mallareddy Adla, Venkat Reddy Papagari, Rasheed Tamboli Jaki
  • Substituted 4-?-acrylamidopodophyllotoxin congeners as antitumour antibiotics and the process for preparation thereof
    Patent number: 8673969
    Abstract: The present invention provides compounds of general formula (3) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis of 4?-acrylamidopodophyllotoxin congeners of general formula (3), wherein R and R1 are an aryl group and R is selected from 3,4,5-trimethoxyphenyl or 2-methoxy phenyl and R1 is selected from the group consisting of 4-hydroxy-3-methoxyphenyl, 3-hydroxy-4-methoxyphenyl, 4-fluoro-3-methoxyphenyl, 3-fluoro-4-methoxyphenyl, 2-fluoro-5-methoxyphenyl, 2-fluoro-4-methoxyphenyl, 4-hydroxy-3-nitrophenyl, 4-methoxy-3-nitrophenyl, 4-nitrophenyl, 3-nitrophenyl, 2-nitro phenyl, 4-methoxyphenyl, 3-methoxyphenyl and 4-hydroxyphenyl.
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: March 18, 2014
    Assignee: Council of Scientific & Industrial Research
    Inventors: Kamal Ahmed, Suresh Paidakula, Ashwini Kumar Banala, Adla Malla Reddy, Papagiri Venkat Reddy
  • 4-AZA-2, 3-DIDEHYDROPODOPHYLLOTOXIN COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20130245048
    Abstract: The present invention provides 4-Aza-2,3-didehydropodophyllotoxin compound of general formula A (4a-4z and 4aa-4ae) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis of 4-Aza-2,3-didehydropodophyllotoxin compounds (4a-4z and 4aa-4ae).
    Type: Application
    Filed: March 25, 2011
    Publication date: September 19, 2013
    Applicant: Council of Scientific & Industrial Research
    Inventors: Kamal Ahmed, Suresh Paidakula, Ashwini Kumar Banala, Mallareddy Adla, Venkat Reddy Papagari, Rasheed Tamboli Jaki
  • SUBSTITUTED 4-BETA-ACRYLAMIDOPODOPHYLLOTOXIN CONGENERS AS ANTITUMOUR ANTIBIOTICS AND THE PROCESS FOR PREPARATION THEREOF
    Publication number: 20130225672
    Abstract: The present invention provides compounds of general formula (3) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis of 4?-acrylamidopodophyllotoxin congeners of general formula (3), wherein R and R1 are an aryl group and R is selected from 3,4,5-trimethoxyphenyl or 2-methoxy phenyl and R1 is selected from the group consisting of 4-hydroxy-3-methoxyphenyl, 3-hydroxy-4-methoxyphenyl, 4-fluoro-3-methoxyphenyl, 3-fluoro-4-methoxyphenyl, 2-fluoro-5-methoxyphenyl, 2-fluoro-4-methoxyphenyl, 4-hydroxy-3-nitrophenyl, 4-methoxy-3-nitrophenyl, 4-nitrophenyl, 3-nitrophenyl, 2-nitro phenyl, 4-methoxyphenyl, 3-methoxyphenyl and 4-hydroxyphenyl.
    Type: Application
    Filed: March 9, 2011
    Publication date: August 29, 2013
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Kamal Ahmed, Suresh Paidakula, Ashwini Kumar Banala, Adla Malla Reddy, Papagiri Venkat Reddy
  • 4?-amino podophyllotoxin congeners as anti tumour antibiotics a process for the preparation thereof
    Patent number: 8354547
    Abstract: The present invention provides novel ?-amino podophyllotoxin congeners of general formula (A); R=CH3, or H; R1=(a) or (b) or (c) or (d) or (e) or (f). The present invention also provides a process for the preparation of 4?-amino podophyllotoxin congeners useful as antitumour agents.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: January 15, 2013
    Assignee: Council of Scientific & Industrial Research
    Inventors: Kamal Ahmed, Ashwini Kumar Banala, Suresh Paidakula
  • NOVEL 4BETA-AMINO PODOPHYLLOTOXIN CONGENERS AS ANTI TUMOUR ANTIBIOTICS A PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20110213165
    Abstract: The present invention provides novel ?-amino podophyllotoxin congeners of general formula (A); R?CH3, or H; R1=(a) or (b) or (c) or (d) or (e) or (f). The present invention also provides a process for the preparation of 4?-amino podophyllotoxin congeners useful as antitumour agents.
    Type: Application
    Filed: March 24, 2009
    Publication date: September 1, 2011
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Kamal Ahmed, Ashwini Kumar Banala, Suresh Paidakula
  • 4?-amino podophyllotoxin congeners as potential anticancer agents and a process for the preparation thereof
    Patent number: 7960418
    Abstract: The present invention provides new class of 4?-[4?-(1?,3?-benzothiazole-2?-yl)anilino]podophyllotoxin analogues having the structural formula as follows (4). Where R?H or CH3; R1?H, halogen, CH3 and R2?H, halogen, OCH3. The present invention also provides a process for the preparation of new 4?-[4?-(1?, 3?-benzothiazole-2?-yl)anilino]podophyllotoxin analogues as useful anticancer agents. More particularly, it provides a process for the preparation of 4?-[4?-(1?,3?-benzothiazole-2?-yl)anilino] derivatives of podophyllotoxin. The process for the synthesis of new podophyllotoxin analogues as anticancer agents produces the novel and stereo-selective derivatives of the podophyllotoxin in good yields, where in the key step for the synthesis of these analogues is by direct nucleophilic substitution of C-4?-iodo intermediates.
    Type: Grant
    Filed: April 30, 2008
    Date of Patent: June 14, 2011
    Assignee: Council of Scientific & Industrial Research
    Inventors: Kamal Ahmed, Ashwini Kumar Banala
  • NOVEL 4BETA-AMINO PODOPHYLLOTOXIN CONGENERS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20080275248
    Abstract: The present invention provides new class of 4?-[4?-(1?,3?-benzothiazole-2?-yl)anilino]podophyllotoxin analogues having the structural formula as follows (4). Where R?H or CH3; R1?H, halogen, CH3 and R2?H, halogen, OCH3. The present invention also provides a process for the preparation of new 4?-[4?-(1?, 3?-benzothiazole-2?-yl)anilino]podophyllotoxin analogues as useful anticancer agents. More particularly, it provides a process for the preparation of 4?-[4?-(1?,3?-benzothiazole-2?-yl)anilino] derivatives of podophyllotoxin. The process for the synthesis of new podophyllotoxin analogues as anticancer agents produces the novel and stereo-selective derivatives of the podophyllotoxin in good yields, where in the key step for the synthesis of these analogues is by direct nucleophilic substitution of C-4?-iodo intermediates.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 6, 2008
    Inventors: Kamal Ahmed, Ashwini Kumar Banala