Abstract: A system for transferring data between asynchronous domains in an SOC includes a slave request generation and data latch circuit, a busy signal generator, a positive edge detector, and a cascaded synchronizer. A host device transmits a host request signal and host data to the slave request generation and data latch circuit for execution by a slave device, which operates at a different frequency than the host device. The slave request generation and data latch circuit stores the host data and transmits it to the slave device based on a synchronized slave clock signal. The host device can perform other tasks while the slave device executes the host request.