Patents by Inventor Asimina Evangelinos

Asimina Evangelinos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060019939
    Abstract: The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.
    Type: Application
    Filed: April 13, 2005
    Publication date: January 26, 2006
    Inventors: Julian Adams, Yun Gao, Asimina Evangelinos, Louis Grenier, Roger Pak, James Porter, James Wright
  • Publication number: 20060019941
    Abstract: The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.
    Type: Application
    Filed: July 13, 2005
    Publication date: January 26, 2006
    Applicant: Infinity Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yun Gao, Asimina Evangelinos, Louis Grenier, Roger Pak, James Porter, James Wright
  • Publication number: 20050227955
    Abstract: The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where the benzoquinone is reduced to a hydroquinone and trapped by reaction with a suitable acid, preferably ones that increase the solubility and air stability of the resulting 17-ammonium hydroquinone ansamycin analog.
    Type: Application
    Filed: December 23, 2004
    Publication date: October 13, 2005
    Inventors: Julian Adams, Yun Gao, Asimina Evangelinos, Louis Grenier, Roger Pak, James Porter, James Wright