Patents by Inventor Asish B. Chakraborty

Asish B. Chakraborty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of charge reduction of electron transfer dissociation product ions
    Patent number: 10490394
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: November 26, 2019
    Assignee: MICROMASS UK LIMITED
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method of Charge Reduction of Electron Transfer Dissociation Product Ions
    Publication number: 20180012743
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Application
    Filed: September 11, 2017
    Publication date: January 11, 2018
    Inventors: Weibin CHEN, Asish B. CHAKRABORTY, John Charles GEBLER, Jeffery Mark BROWN
  • Method of charge reduction of electron transfer dissociation product ions
    Patent number: 9761425
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: September 12, 2017
    Assignee: Micromass UK Limited
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method of Charge Reduction of Electron Transfer Dissociation Product Ions
    Publication number: 20150294846
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Application
    Filed: June 26, 2015
    Publication date: October 15, 2015
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method of charge reduction of electron transfer dissociation product ions
    Patent number: 9070539
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: June 30, 2015
    Assignee: Micromass UK Limited
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Techniques for efficient fragmentation of peptides
    Patent number: 8921773
    Abstract: Techniques are described for performing mass spectrometry. A stream of one or more ions is generated. The stream is transmitted into a collision cell over a period of time. In accordance with a set of criteria including a retention time of one or more precursor ions, a collision energy of the collision cell is selected to generate one or more product ions for said one or more precursor ions in said stream.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: December 30, 2014
    Assignee: Waters Technologies Corporation
    Inventors: Scott J. Geromanos, Johannes P. C. Vissers, Craig A. Dorschel, Asish B. Chakraborty, Welbin Chen, Jeffrey Cruz Silva
  • Method of Charge Reduction of Electron Transfer Dissociation Product Ions
    Publication number: 20140110576
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Application
    Filed: December 31, 2013
    Publication date: April 24, 2014
    Applicant: Micromass UK Limited
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Method of charge reduction of electron transfer dissociation product ions
    Patent number: 8624179
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell 35 by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: January 7, 2014
    Assignee: Micromass UK Limited
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • TECHNIQUES FOR EFFICIENT FRAGMENTATION OF PEPTIDES
    Publication number: 20130105682
    Abstract: Techniques are described for performing mass spectrometry. A stream of one or more ions is generated. The stream is transmitted into a collision cell over a period of time. In accordance with a set of criteria including a retention time of one or more precursor ions, a collision energy of the collision cell is selected to generate one or more product ions for said one or more precursor ions in said stream.
    Type: Application
    Filed: January 19, 2011
    Publication date: May 2, 2013
    Applicant: Waters Technologies Corporation
    Inventors: Scott J. Geromanos, Johannes P.C. Vissers, Craig A. Dorschel, Asish B. Chakraborty, Welbin Chen, Jeffrey Cruz Silva
  • Method Of Charge Reduction Of Electron Transfer Dissociation Product Ions
    Publication number: 20110114835
    Abstract: A mass spectrometer is disclosed wherein highly charged fragment ions resulting from Electron Transfer Dissociation fragmentation of parent ions are reduced in charge state within a Proton Transfer Reaction cell 35 by reacting the fragment ions with a neutral superbase reagent gas such as Octahydropyrimidolazepine.
    Type: Application
    Filed: June 5, 2009
    Publication date: May 19, 2011
    Applicant: MICROMASS UK LIMITED
    Inventors: Weibin Chen, Asish B. Chakraborty, John Charles Gebler, Jeffery Mark Brown
  • Affinity selected signature peptides for protein identification and quantification
    Publication number: 20030092076
    Abstract: A method for protein identification in complex mixtures that utilizes affinity selection of constituent proteolytic peptide fragments unique to a protein analyte. These “signature peptides” function as analytical surrogates. Mass spectrometric analysis of the proteolyzed mixture permits identification of a protein in a complex sample without purifying the protein or obtaining its composite peptide signature.
    Type: Application
    Filed: September 16, 2002
    Publication date: May 15, 2003
    Applicant: Purdue Research Foundation
    Inventors: Fred E. Regnier, Xiang Zhang, Asish B. Chakraborty