Patents by Inventor Asit Panja

Asit Panja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use and identification of biomarkers for gastrointestinal diseases
    Patent number: 10087488
    Abstract: The described invention relates to the identification of biomarkers for gastrointestinal diseases and provides methods utilizing the biomarkers for in drug discovery, monitoring of treatment efficacy, and diagnostics. The invention further provides methods for identifying a therapeutic target to treat ulcerative colitis, colorectal cancer, and Crohn's disease.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: October 2, 2018
    Assignee: AlfaGene Bioscience, Inc.
    Inventor: Asit Panja
  • USE AND IDENTIFICATION OF BIOMARKERS FOR GASTROINTESTINAL DISEASES
    Publication number: 20160312290
    Abstract: The described invention relates to the identification of biomarkers for gastrointestinal diseases and provides methods utilizing the biomarkers for in drug discovery, monitoring of treatment efficacy, and diagnostics. The invention further provides methods for identifying a therapeutic target to treat ulcerative colitis, colorectal cancer, and Crohn's disease.
    Type: Application
    Filed: February 22, 2016
    Publication date: October 27, 2016
    Applicant: AlfaGene Bioscience, Inc.
    Inventor: Asit PANJA
  • DRUG DISCOVERY METHODS INVOLVING A PRECLNICAL, IN VITRO ISOLATED GASTROINTESTINAL EPITHELIAL STEM CELL-LIKE PROGENITOR CELL SYSTEM
    Publication number: 20160084824
    Abstract: The described invention relate to systems comprising isolated human gastrointestinal segment-specific epithelial stem cell-like progenitor cells and uses thereof in drug discovery.
    Type: Application
    Filed: September 1, 2015
    Publication date: March 24, 2016
    Applicant: ALFAGENE BIOSCIENCE, INC.
    Inventor: Asit PANJA
  • Use and identification of biomarkers for gastrointestinal diseases
    Patent number: 9267935
    Abstract: The described invention relates to the identification of biomarkers for gastrointestinal diseases and provides methods utilizing the biomarkers for in drug discovery, monitoring of treatment efficacy, and diagnostics. The invention further provides methods for identifying a therapeutic target to treat ulcerative colitis, colorectal cancer, and Crohn's disease.
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: February 23, 2016
    Assignee: AlfaGene Bioscience, Inc.
    Inventor: Asit Panja
  • Human gastrointestinal stem cell-derived primary intestinal epithelial cell system and methods of use thereof
    Patent number: 9212382
    Abstract: The present invention relates to an intestinal primary epithelial cell system for detecting gastrointestinal segment-specific activation or suppression of a Toll-like receptor (TLR) by a target agent. The cell system includes an isolated human intestinal primary epithelial cell (HIPEC) line that expresses at least one TLR, where the HIPEC line is derived from a differentiable adult human gastrointestinal stem cell (ahGISC) line. Also disclosed are various methods of using the cell system, a kit that includes the cell system, and an isolated cell culture including an isolated HIPEC line derived from a differentiable ahGISC line.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: December 15, 2015
    Assignee: AlfaGene Bioscience, Inc.
    Inventor: Asit Panja
  • USE AND IDENTIFICATION OF BIOMARKERS FOR GASTROINTESTINAL DISEASES
    Publication number: 20130303398
    Abstract: The described invention relates to the identification of biomarkers for gastrointestinal diseases and provides methods utilizing the biomarkers for in drug discovery, monitoring of treatment efficacy, and diagnostics. The invention further provides methods for identifying a therapeutic target to treat ulcerative colitis, colorectal cancer, and Crohn's disease.
    Type: Application
    Filed: July 22, 2013
    Publication date: November 14, 2013
    Inventor: Asit PANJA
  • Human gastrointestinal stem cell-derived primary intestinal epithelial cell system and methods of use thereof
    Patent number: 8367316
    Abstract: The present invention relates to an intestinal primary epithelial cell system for detecting gastrointestinal segment-specific activation or suppression of a Toll-like receptor (TLR) by a target agent. The cell system includes an isolated human intestinal primary epithelial cell (HIPEC) line that expresses at least one TLR, where the HIPEC line is derived from a differentiable adult human gastrointestinal stem cell (ahGISC) line. Also disclosed are various methods of using the cell system, a kit that includes the cell system, and an isolated cell culture including an isolated HIPEC line derived from a differentiable ahGISC line.
    Type: Grant
    Filed: May 3, 2010
    Date of Patent: February 5, 2013
    Assignee: AlfaGene Bioscience, Inc.
    Inventor: Asit Panja
  • HUMAN GASTROINTESTINAL STEM CELL-DERIVED PRIMARY INTESTINAL EPITHELIAL CELL SYSTEM AND METHODS OF USE THEREOF
    Publication number: 20100279275
    Abstract: The present invention relates to an intestinal primary epithelial cell system for detecting gastrointestinal segment-specific activation or suppression of a Toll-like receptor (TLR) by a target agent. The cell system includes an isolated human intestinal primary epithelial cell (HIPEC) line that expresses at least one TLR, where the HIPEC line is derived from a differentiable adult human gastrointestinal stem cell (ahGISC) line. Also disclosed are various methods of using the cell system, a kit that includes the cell system, and an isolated cell culture including an isolated HIPEC line derived from a differentiable ahGISC line.
    Type: Application
    Filed: May 3, 2010
    Publication date: November 4, 2010
    Applicant: ALFAGENE BIOSCIENCE, INC.
    Inventor: Asit PANJA
  • USE AND IDENTIFICATION OF BIOMARKERS FOR GASTROINTESTINAL DISEASES
    Publication number: 20100093552
    Abstract: The described invention relates to the identification of biomarkers for gastrointestinal diseases and provides methods utilizing the biomarkers for in drug discovery, monitoring of treatment efficacy, and diagnostics. The invention further provides methods for identifying a therapeutic target to treat ulcerative colitis, colorectal cancer, and Crohn's disease.
    Type: Application
    Filed: October 9, 2009
    Publication date: April 15, 2010
    Inventor: Asit Panja
  • Drug Discovery Methods Involving A Preclinical, In Vitro Isolated Gastrointestinal Epithelial Stem Cell-Like Progenitor Cell System
    Publication number: 20090269769
    Abstract: The described invention relate to systems comprising isolated human gastrointestinal segment-specific epithelial stem cell-like progenitor cells and uses thereof in drug discovery.
    Type: Application
    Filed: April 23, 2009
    Publication date: October 29, 2009
    Inventor: Asit Panja