Patents by Inventor Ask Puschl

Ask Puschl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-ARYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS
    Publication number: 20120302548
    Abstract: This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
    Type: Application
    Filed: December 15, 2010
    Publication date: November 29, 2012
    Applicant: H. LUNDBECK A/S
    Inventors: Ask Püschl, Jacob Nielsen, Jan Kehler, John Paul Kilburn, Mauro Marigo, Morten Langgård
  • PHENYL-PIPERAZINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS
    Publication number: 20120302553
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: February 6, 2012
    Publication date: November 29, 2012
    Applicant: H. LUNDBECK A/S
    Inventors: Thomas Ruhland, Garrick P. Smith, Benny Bang-Anderson, Ask Puschl, Ejner Knud Moltzen, Kim Andersen
  • METHODS OF ADMINISTERING (4AR,10AR)-1-N-PROPYL-1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO [G] QUINOLINE-6,7-DIOL AND RELATED COMPOUNDS ACROSS THE ORAL MUCOSA, THE NASAL MUCOSA OR THE SKIN AND PHARMACEUTICAL COMPOSITIONS THEREOF
    Publication number: 20120077836
    Abstract: Disclosed are pharmaceutical compositions and methods for the administration of (4aR,10aR)-1-n-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinoline-6,7-diol or a pharmaceutically acceptable salt thereof and related compounds for the treatment of neurological disorder such as Parkinson's disease and restless leg syndrome.
    Type: Application
    Filed: February 26, 2010
    Publication date: March 29, 2012
    Applicant: H. LUNDBECK A/S
    Inventors: Håkan Wikström, Morten Jorgensen, Niels Mork, Jennifer Larsen, Benny Bang-Andersen, Thomas Nikolaj Sager, Ask Püschl, Lars Torup
  • Catecholamine derivatives and prodrugs thereof
    Patent number: 8129530
    Abstract: The present invention relates to novel catecholamine derivatives of Formula I, to processes for their preparation, pharmaceutical compositions containing them and to their use in therapy.
    Type: Grant
    Filed: August 19, 2008
    Date of Patent: March 6, 2012
    Assignee: H. Lundbeck A/S
    Inventors: Morten Jorgensen, Benny Bang-Andersen, Ask Puschl, Niels Mork, Jennifer Larsen
  • Phenyl-piperazine derivatives as serotonin reuptake inhibitors
    Patent number: 8110567
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: February 7, 2012
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ejner Knud Moltzen, Kim Andersen, Ask Puschl
  • Phenolic and catecholic amines and prodrugs thereof
    Patent number: 8067410
    Abstract: The present invention relates to novel phenolic and catecholic amines of Formula I, to processes for their preparation, pharmaceutical compositions containing them, to their use in therapy and to their use in radiolabeled form as PET- or SPECT ligands.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: November 29, 2011
    Assignee: H. Lundbeck A/S
    Inventors: Ask Puschl, Morten Jorgensen, Benny Bang-Andersen
  • PHENYL-PIPERAZINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS
    Publication number: 20110009423
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: February 4, 2010
    Publication date: January 13, 2011
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick P. Smith, Benny Bang-Andersen, Ask Puschl, Ejner K. Moltzen, Kim Andersen
  • 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors
    Patent number: 7732463
    Abstract: The invention provides compounds represented by the general formula (I) wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: June 8, 2010
    Assignee: H. Lundbeck A/S
    Inventors: Ask Puschl, Benny Bang-Andersen, Morten Jorgensen, Thomas Ruhland, Tine B. Stensbol
  • NOVEL PHENOLIC AND CATECHOLIC AMINES AND PRODRUGS THEREOF
    Publication number: 20090325946
    Abstract: The present invention relates to novel phenolic and catecholic amines of Formula I, to processes for their preparation, pharmaceutical compositions containing them, to their use in therapy and to their use in radiolabeled form as PET- or SPECT ligands.
    Type: Application
    Filed: June 24, 2009
    Publication date: December 31, 2009
    Applicant: H. Lundbeck A/S
    Inventors: Ask PUSCHL, Morten JORGENSEN, Benny BANG-ANDERSEN
  • Indane compounds
    Patent number: 7618967
    Abstract: The invention provides novel indane compounds which are useful in the treatment of affective disorders, pain disorders, attention deficit hyperactivity disorder (ADHD), cognitive disorders, substance abuse, smoking cessation and stress urinary incontinence.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: November 17, 2009
    Assignee: H. Lundbeck A/S
    Inventors: Jan Kehler, Karsten Juhl, Ask Püschl
  • USES OF INDANE COMPOUNDS
    Publication number: 20090215774
    Abstract: The invention provides methods of treating obesity and eating disorders, which comprise administering indane compounds of Formula (I): where R1-R6, m and n are defined herein.
    Type: Application
    Filed: February 22, 2009
    Publication date: August 27, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Jan Kehler, Karsten Juhl, Ask Puschl
  • CATECHOLAMINE DERIVATIVES AND PRODRUGS THEREOF
    Publication number: 20090124651
    Abstract: The present invention relates to novel catecholamine derivatives of Formula I, to processes for their preparation, pharmaceutical compositions containing them and to their use in therapy.
    Type: Application
    Filed: August 19, 2008
    Publication date: May 14, 2009
    Applicant: H. LUNDBECK A/S
    Inventors: Morten Jorgensen, Benny Bang- Andersen, Ask Puschl, Niels Mork, Jennifer Larsen, Hakan Vilhelm Wikstrom
  • CATECHOLAMINE DERIVATIVES AND PRODRUGS THEREOF
    Publication number: 20090062324
    Abstract: The present invention relates to novel catecholamine derivatives of Formula I, to processes for their preparation, pharmaceutical compositions containing them and to their use in therapy.
    Type: Application
    Filed: August 19, 2008
    Publication date: March 5, 2009
    Applicant: H. Lundbeck A/S
    Inventors: Morten Jorgensen, Benny Bang- Andersen, Ask Puschl, Niels Mork, Jennifer Larsen
  • Aminoindane Derivatives As Serotonin And Norepinephrine Uptake Inhibitors
    Publication number: 20080119547
    Abstract: The present invention relates to aminoindane derivatives having the formula I wherein X, Y, U, R1-2, and R13-16 are as defined in the claims, or an acid addition salt thereof. The compounds of the invention posses the combined effect of serotonin reuptake inhibition and norepinephrine uptake inhibition.
    Type: Application
    Filed: January 9, 2008
    Publication date: May 22, 2008
    Applicant: H. Lundbeck A/S
    Inventors: Klaus Peter Bogeso, Ask Puschl, Jan Kehler
  • Aminoindane derivatives as serotonin and norepinephrine uptake inhibitors
    Patent number: 7351734
    Abstract: The present invention relates to aminoindane derivatives having the formula I wherein X, Y, U, R1-2, R13-16 and R are as defined in the claims, or an acid addition salt thereof. The compounds of the invention posses the combined effect of serotonin reuptake inhibition and norepinephrine uptake inhibition.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: April 1, 2008
    Assignee: H. Lundbeck A/S
    Inventors: Klaus Peter Bøgesø, Ask Püschl, Jan Kehler, Peter Bregnedal
  • NOVEL INDANE COMPOUNDS
    Publication number: 20080058329
    Abstract: The invention provides novel indane compounds which are useful in the treatment of affective disorders, pain disorders, attention deficit hyperactivity disorder (ADHD), cognitive disorders, substance abuse, smoking cessation and stress urinary incontinence.
    Type: Application
    Filed: August 30, 2007
    Publication date: March 6, 2008
    Applicant: H. Lundbeck A/S
    Inventors: Jan Kehler, Karsten Juhl, Ask Puschl
  • 4-(2-Phenylsulfanyl-phenyl)-1,2,3,6- tetrahydropyridine derivatives as serotonin reuptake inhibitors
    Publication number: 20070173522
    Abstract: The invention provides compounds represented by the general formula (I) wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: April 2, 2004
    Publication date: July 26, 2007
    Inventors: Ask Puschl, Benny Bang-Andersen, Morten Jorgensen, Karsten Juhl, Thomas Ruhland, Kim Andersen, Jan Kehler
  • PHENYL-PIPERAZINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS
    Publication number: 20070060574
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Application
    Filed: October 19, 2006
    Publication date: March 15, 2007
    Applicant: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Smith, Benny Bang-Andersen, Ask Puschl, Ejner Moltzen, Kim Andersen
  • Phenyl-piperazine derivatives as serotonin reuptake inhibitors
    Patent number: 7148238
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: December 12, 2006
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Benny Bang-Andersen, Ask Puschl
  • Phenyl-piperazine derivatives as serotonin reuptake inhibitors
    Patent number: 7144884
    Abstract: The invention provides compounds represented by the general formula I wherein the substituents are defined in the application.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: December 5, 2006
    Assignee: H. Lundbeck A/S
    Inventors: Thomas Ruhland, Garrick Paul Smith, Benny Bang-Andersen, Ask Puschl, Ejner Knud Moltzen, Kim Andersen