Patents by Inventor Asma Hatoum

Asma Hatoum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crispr-CAS10 systems and methods for phage genome editing
    Patent number: 12378577
    Abstract: The present disclosure relates to CRISPR-Cas10 systems and methods for phage genome editing.
    Type: Grant
    Filed: September 16, 2022
    Date of Patent: August 5, 2025
    Assignee: The Board of Trustees of The University of Alabama
    Inventor: Asma Hatoum
  • Methods and devices related to controlled delivery of phages as a theranostic tool
    Patent number: 11667895
    Abstract: Disclosed herein is an engineered bacteriophage comprising an indicator gene, wherein said indicator gene is an RNA aptamer or a green fluorescent protein (GFP) or GFP-like protein, and further wherein said indicator gene can indicate the presence of a microorganism, such as a bacterial infection. The engineered bacteriophage can be capable of infecting and killing the microorganism. The engineered microorganism can be in a composition for delivery to a subject, and can be in hyaluronic acid, for example. Also disclosed are methods of using the engineered bacteriophage to diagnose and/or treat a subject with a bacterial infection.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: June 6, 2023
    Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA
    Inventors: Asma Hatoum, Shreyas Rao
  • CRISPR-CAS10 SYSTEMS AND METHODS FOR PHAGE GENOME EDITING
    Publication number: 20230041099
    Abstract: The present disclosure relates to CRISPR-Cas10 systems and methods for phage genome editing.
    Type: Application
    Filed: September 16, 2022
    Publication date: February 9, 2023
    Inventor: Asma Hatoum
  • Crispr-CAS10 systems and methods for phage genome editing
    Patent number: 11453892
    Abstract: The present disclosure relates to CRISPR-Cas10 systems and methods for phage genome editing.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: September 27, 2022
    Assignee: The Board of Trustees of The University of Alabama
    Inventor: Asma Hatoum
  • METHODS AND DEVICES RELATED TO CONTROLLED DELIVERY OF PHAGES AS A THERANOSTIC TOOL
    Publication number: 20200354689
    Abstract: Disclosed herein is an engineered bacteriophage comprising an indicator gene, wherein said indicator gene is an RNA aptamer or a green fluorescent protein (GFP) or GFP-like protein, and further wherein said indicator gene can indicate the presence of a microorganism, such as a bacterial infection. The engineered bacteriophage can be capable of infecting and killing the microorganism. The engineered microorganism can be in a composition for delivery to a subject, and can be in hyaluronic acid, for example. Also disclosed are methods of using the engineered bacteriophage to diagnose and/or treat a subject with a bacterial infection.
    Type: Application
    Filed: May 4, 2020
    Publication date: November 12, 2020
    Inventors: Asma Hatoum, Shreyas Rao
  • CRISPR-CAS10 SYSTEMS AND METHODS FOR PHAGE GENOME EDITING
    Publication number: 20180251787
    Abstract: The present disclosure relates to CRISPR-Cas10 systems and methods for phage genome editing.
    Type: Application
    Filed: March 2, 2018
    Publication date: September 6, 2018
    Inventor: Asma Hatoum