Patents by Inventor Assaf COHEN-DOTAN

Assaf COHEN-DOTAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11883825
    Abstract: In a cartridge device for analyzing a body liquid, a first member of the cartridge has two or more wells for performing assays, and a second member of the cartridge has a compartment for holding one or more disposable pipette tips.
    Type: Grant
    Filed: September 2, 2018
    Date of Patent: January 30, 2024
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Noga Salomon, Kfir Oved, Yana Khalfin, Omer Nahum Katzenelson, Amir Gelman, Moran Brouk Rudich, Roy Navon, Assaf Cohen-Dotan, Eran Eden, Salit Tzaban, Arnon Zangvil, Ofer Halbreich, Matthew Fenwick, Adrian Charles Ian Scott-Murphy, Matthew Hou-Pou Yeung, James William Luther, Barbara Tornaghi, Andrea Besana, Thomas Sanelli Crugnale
  • Publication number: 20240029818
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Application
    Filed: August 7, 2023
    Publication date: January 25, 2024
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Roy NAVON, Assaf COHEN-DOTAN, Olga BOICO
  • Patent number: 11776658
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Grant
    Filed: July 28, 2022
    Date of Patent: October 3, 2023
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Roy Navon, Assaf Cohen-Dotan, Olga Boico
  • Publication number: 20230204568
    Abstract: A method of measuring the amount of TNF-related apoptosis-inducing ligand (TRAIL) polypeptide in a fluid sample of a subject in need thereof is disclosed. The method uses a lateral flow immunoassay (LFT) device.
    Type: Application
    Filed: February 20, 2023
    Publication date: June 29, 2023
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Kfir OVED, Eran EDEN, BOICO Olga, Gali KRONENFELD, Roy NAVON, Assaf COHEN-DOTAN
  • Publication number: 20230184760
    Abstract: A method of determining an infection type in a subject is disclosed. The method comprises measuring the concentration of a first determinant selected from the group consisting of the determinants which are set forth in Table 1 and a second determinant selected from the group of the determinants which are set forth in Table 2 in a subject derived sample, wherein the concentration is indicative of the infection type.
    Type: Application
    Filed: December 8, 2022
    Publication date: June 15, 2023
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Kfir OVED, Eran EDEN, Gali KRONENFELD, Olga BOICO, Roy NAVON, Assaf COHEN-DOTAN
  • Publication number: 20230045305
    Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of a determinant which is set forth in Tables 1 or 2 in a sample derived from the subject, wherein said amount is indicative of the infection type.
    Type: Application
    Filed: September 29, 2022
    Publication date: February 9, 2023
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Kfir OVED, Eran EDEN, Olga BOICO, Gali KRONENFELD, Roy NAVON, Assaf COHEN-DOTAN, Einav SIMON
  • Publication number: 20220399074
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Application
    Filed: July 28, 2022
    Publication date: December 15, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Roy NAVON, Assaf COHEN-DOTAN, Olga BOICO
  • Publication number: 20220326256
    Abstract: A method of determining a management course for treating a subject showing symptoms of a disease is disclosed. The method comprises measuring the TRAIL protein level in a blood sample of the subject, wherein when the TRAIL level is below a predetermined amount, the subject is treated as a high-risk patient.
    Type: Application
    Filed: June 16, 2022
    Publication date: October 13, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Assaf COHEN-DOTAN, Roy NAVON, Olga BOICO, Meital PAZ
  • Publication number: 20220326238
    Abstract: A method of measuring risk assessment in a patient with appendicitis is disclosed. The method comprises: (a) measuring the TRAIL protein level in a blood sample of the patient; and (b) providing a risk assessment based on the TRAIL protein level.
    Type: Application
    Filed: June 5, 2022
    Publication date: October 13, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Kfir OVED, Eran EDEN, Assaf COHEN-DOTAN, Roy NAVON, Niv Steven MASTBOIM, Olga BOICO, Meital PAZ
  • Patent number: 11466331
    Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of a determinant which is set forth in Tables 1 or 2 in a sample derived from the subject, wherein said amount is indicative of the infection type.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: October 11, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Kfir Oved, Eran Eden, Olga Boico, Gali Kronenfeld, Roy Navon, Assaf Cohen-Dotan, Einav Simon
  • Patent number: 11450406
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Grant
    Filed: August 20, 2020
    Date of Patent: September 20, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Roy Navon, Assaf Cohen-Dotan, Olga Boico
  • Publication number: 20220236269
    Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of TRAIL and/or IP10 no more than two days from symptom onset.
    Type: Application
    Filed: April 11, 2022
    Publication date: July 28, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Assaf COHEN-DOTAN, Roy NAVON, Olga BOICO, Meital PAZ
  • Patent number: 11385241
    Abstract: A method of determining a management course for treating a subject showing symptoms of a disease is disclosed. The method comprises measuring the TRAIL protein level in a blood sample of the subject, wherein when the TRAIL level is below a predetermined amount, the subject is treated as a high-risk patient.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: July 12, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Assaf Cohen-Dotan, Roy Navon, Olga Boico, Meital Paz
  • Patent number: 11353456
    Abstract: A method of measuring risk assessment in a patient with appendicitis is disclosed. The method comprises: (a) measuring the TRAIL protein level in a blood sample of the patient; (b) providing a risk assessment based on the TRAIL protein level.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: June 7, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Kfir Oved, Eran Eden, Assaf Cohen-Dotan, Roy Navon, Niv Steven Mastboim, Olga Boico, Meital Paz
  • Patent number: 11340223
    Abstract: Methods of determining infection type are disclosed. In one embodiment, the method comprises measuring the amount of TRAIL and/or IP10 no more than two days from symptom onset.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: May 24, 2022
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Assaf Cohen-Dotan, Roy Navon, Olga Boico, Meital Paz
  • Publication number: 20220011320
    Abstract: Methods of diagnosing infections are disclosed. In one embodiment, the method comprises measuring the amount of each of the polypeptides TRAIL, CRP, IP10 and at least one additional polypeptide selected from the group consisting of IL-6 and PCT.
    Type: Application
    Filed: July 12, 2021
    Publication date: January 13, 2022
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Assaf COHEN-DOTAN, Roy NAVON, Olga BOICO, Gali KRONENFELD, Meital PAZ, Ellen BAMBERGER
  • Patent number: 11131671
    Abstract: Methods of diagnosing infections are disclosed. In one embodiment, the method comprises measuring the amount of each of the polypeptides TRAIL, CRP, IP10 and at least one additional polypeptide selected from the group consisting of IL-6 and PCT.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: September 28, 2021
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Assaf Cohen-Dotan, Roy Navon, Olga Boico, Gali Kronenfeld, Meital Paz, Ellen Bamberger
  • Patent number: 11081206
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: August 3, 2021
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Eran Eden, Kfir Oved, Roy Navon, Assaf Cohen-Dotan, Olga Boico
  • Publication number: 20200393463
    Abstract: A method of determining an infection type in a subject is disclosed. The method comprises measuring the concentration of a first determinant selected from the group consisting of the determinants which are set forth in Table 1 and a second determinant selected from the group of the determinants which are set forth in Table 2 in a subject derived sample, wherein the concentration is indicative of the infection type.
    Type: Application
    Filed: August 31, 2020
    Publication date: December 17, 2020
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Kfir OVED, Eran EDEN, Gali KRONENFELD, Olga BOICO, Roy NAVON, Assaf COHEN-DOTAN
  • Publication number: 20200388347
    Abstract: A method of analyzing biological data containing expression values of a plurality of polypeptides in the blood of a subject. The method comprises: calculating a distance between a segment of a curved line and an axis defined by a direction, the distance being calculated at a point over the curved line defined by a coordinate along the direction. The method further comprises correlating the distance to the presence of, absence of, or likelihood that the subject has, a bacterial infection. The coordinate is defined by a combination of the expression values, wherein at least 90% of the segment is between a lower bound line and an upper bound line.
    Type: Application
    Filed: August 20, 2020
    Publication date: December 10, 2020
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Eran EDEN, Kfir OVED, Roy NAVON, Assaf COHEN-DOTAN, Olga BOICO