Patents by Inventor Assaf KACEN

Assaf KACEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AGENTS BINDING MODIFIED ANTIGEN PRESENTED PEPTIDES AND USE OF SAME
    Publication number: 20240029819
    Abstract: Agents binding modified antigen dependent peptides and use of same are provided. Accordingly, there is provided an agent capable of specifically binding an MHC presented peptide comprising a post translational modification (PTM), wherein the agent does not bind a peptide having the same amino acid sequence as said peptide but does not comprise said modification. Also provided are polynucleotides encoding the agent, cells expressing same and methods of use thereof. Also provided is a computer implemented method for generating a dataset of PTM on MHC bound peptides.
    Type: Application
    Filed: April 27, 2023
    Publication date: January 25, 2024
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Yifat MERBL, Assaf KACEN, Yishai LEVIN, David MORGENSTERN
  • METHODS OF TREATING AND DIAGNOSING LUNG CANCER
    Publication number: 20220155305
    Abstract: A method of treating lung cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of an agent that downregulates an amount or activity of a polypeptide selected from the group consisting of CASC5, MYOF, CTNS, FCGR2B, PCDHGC5, POMGNT2, ACSL1, CTAGE5, TECPR2, WDR48, MCPH1, PPP2R3C, ADRB1, JAG2, GEMIN7, PTPRB, PRMT9, PSME4, Ube2L3, TP53RK and PSME3.
    Type: Application
    Filed: January 28, 2022
    Publication date: May 19, 2022
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Yifat MERBL, Aaron JAVITT, Assaf KACEN, Avital EISENBERG-LERNER, Merav SHMUELI