Patents by Inventor Assem G. Ziady

Assem G. Ziady has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR OPTIMIZING CFTR-MODULATOR THERAPY
    Publication number: 20240066021
    Abstract: Disclosed are methods for the treatment of cystic fibrosis in an individual in need thereof. The methods may include the administration of a CFTR modulator, with or without and one or more CFTR modulator therapy optimizing agent. Further disclosed are methods for treating cystic fibrosis in an individual in need thereof which employ detection of one or more biomarkers which may be used to distinguish CFTR modulator responders and non-responders, which may in turn be used to direct therapy in an individual having cystic fibrosis.
    Type: Application
    Filed: January 14, 2022
    Publication date: February 29, 2024
    Inventors: Assem G. Ziady, Emily J. Skala, Maureen B. Dunn, Karen Lammers
  • COMPOSITIONS AND METHODS FOR NUCLEIC ACID TRANSFER
    Publication number: 20210102208
    Abstract: Disclosed are methods for the enhancement of nucleic acid delivery systems. The methods may employ treatment with a compound and/or an RNAi molecule in combination with a nucleic acid to improve nucleic acid uptake into a cell. In particular, the disclosed methods may be useful for improved gene therapy techniques.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Inventors: Assem G. Ziady, Matthew Siefert, Songbai Lin, Harrison Brown
  • Compositions and methods for nucleic acid transfer
    Patent number: 10894960
    Abstract: Disclosed are methods for the enhancement of nucleic acid delivery systems. The methods may employ treatment with a compound and/or an RNAi molecule in combination with a nucleic acid to improve nucleic acid uptake into a cell. In particular, the disclosed methods may be useful for improved gene therapy techniques.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: January 19, 2021
    Assignee: Children's Hospital Medical Center
    Inventors: Assem G. Ziady, Matthew Siefert, Songbai Lin, Harrison Brown
  • COMPOSITIONS AND METHODS FOR NUCLEIC ACID TRANSFER
    Publication number: 20180057813
    Abstract: Disclosed are methods for the enhancement of nucleic acid delivery systems. The methods may employ treatment with a compound and/or an RNAi molecule in combination with a nucleic acid to improve nucleic acid uptake into a cell. In particular, the disclosed methods may be useful for improved gene therapy techniques.
    Type: Application
    Filed: August 30, 2017
    Publication date: March 1, 2018
    Inventors: Assem G. Ziady, Matthew Siefert, Songbai Lin, Harrison Brown