Patents by Inventor Astar Winoto

Astar Winoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of an innate immune response by altering TRIAL-R signaling
    Patent number: 7892539
    Abstract: Methods and composition are provided for modulating innate immunity by modulating activation of the TRAIL receptor. Signaling through the TRAIL-R inhibits the responsiveness of cells including dendritic cells, macrophages, and the like. The activity of these cells is increased or decreased by the administration of agents that inhibit or activate TRAIL-R signaling. Innate immunity includes the production of cytokines that act on the immune system.
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: February 22, 2011
    Assignee: The Regents of the University of California
    Inventors: Astar Winoto, Gretchen Elizabeth Diehl, Herman Heng Yue
  • TRAIL-R as a negative regulator of innate immune cell responses
    Publication number: 20050216960
    Abstract: Methods and composition are provided for modulating innate immunity by modulating activation of the TRAIL receptor. Signaling through the TRAIL-R inhibits the responsiveness of cells including dendritic cells, macrophages, and the like. The activity of these cells is increased or decreased by the administration of agents that inhibit or activate TRAIL-R signaling. Innate immunity includes the production of cytokines that act on the immune system.
    Type: Application
    Filed: March 23, 2005
    Publication date: September 29, 2005
    Inventors: Astar Winoto, Gretchen Diehl, Herman Yue