Patents by Inventor Astrid DE GREEFF

Astrid DE GREEFF has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Attenuating bacterial virulence by attenuating bacterial folate transport
    Patent number: 11992522
    Abstract: The invention relates to bacterial infections, vaccines directed against those infections and bacterial vaccines. More particularly, the invention relates to vaccines directed against Streptococcus infections in pigs. The invention provides a ?FolT mutant of a bacterium having reduced capacity to transport folate, wherein said capacity has been reduced by functionally deleting folate transporter (FolT) function. The invention also provides a method to reduce virulence of a bacterium comprising reducing the capacity of said bacterium to transport folate.
    Type: Grant
    Filed: May 12, 2023
    Date of Patent: May 28, 2024
    Inventors: Alaina Ingebritson, Axel Neubauer, Hilda Elizabeth Smith, Astrid De Greeff
  • Attenuating bacterial virulence by attenuating bacterial folate transport
    Publication number: 20240115687
    Abstract: The invention relates to bacterial infections, vaccines directed against those infections and bacterial vaccines. More particularly, the invention relates to vaccines directed against Streptococcus infections in pigs. The invention provides a ?FolT mutant of a bacterium having reduced capacity to transport folate, wherein said capacity has been reduced by functionally deleting folate transporter (FolT) function. The invention also provides a method to reduce virulence of a bacterium comprising reducing the capacity of said bacterium to transport folate.
    Type: Application
    Filed: May 12, 2023
    Publication date: April 11, 2024
    Inventors: Alaina INGEBRITSON, Axel NEUBAUER, Hilda Elizabeth SMITH, Astrid DE GREEFF
  • Attenuating bacterial virulence by attenuating bacterial folate transport
    Patent number: 11684663
    Abstract: The invention relates to bacterial infections, vaccines directed against those infections and bacterial vaccines. More particularly, the invention relates to vaccines directed against Streptococcus infections in pigs. The invention provides a ?FolT mutant of a bacterium having reduced capacity to transport folate, wherein said capacity has been reduced by functionally deleting folate transporter (FolT) function. The invention also provides a method to reduce virulence of a bacterium comprising reducing the capacity of said bacterium to transport folate.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: June 27, 2023
    Inventors: Alaina Ingebritson, Axel Neubauer, Hilda Elizabeth Smith, Astrid De Greeff
  • Attenuating bacterial virulence by attenuating bacterial folate transport
    Publication number: 20220226456
    Abstract: The invention relates to bacterial infections, vaccines directed against those infections and bacterial vaccines. More particularly, the invention relates to vaccines directed against Streptococcus infections in pigs. The invention provides a ?FolT mutant of a bacterium having reduced capacity to transport folate, wherein said capacity has been reduced by functionally deleting folate transporter (FolT) function. The invention also provides a method to reduce virulence of a bacterium comprising reducing the capacity of said bacterium to transport folate.
    Type: Application
    Filed: November 10, 2017
    Publication date: July 21, 2022
    Inventors: Alaina INGEBRITSON, Axel NEUBAUER, Hilda Elizabeth SMITH, Astrid DE GREEFF