Patents by Inventor Astrid Markus

Astrid Markus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040039030
    Abstract: Compounds of the formula (I) are disclosed and are suitable for the treatment of seborrheic dermatitis.
    Type: Application
    Filed: June 26, 2003
    Publication date: February 26, 2004
    Applicant: Hoechst Akeengesellschaft
    Inventors: Manfred Bohn, Karl Theodor Kraemer, Astrid Markus
  • Patent number: 6677429
    Abstract: A compound of Formula I in which R1 and R2=H, OH, alkyl optionally substituted, or NR1 forms with the carbon bearing NR1R2 a double bond and R2 is Xra, X being O, NH or N-alkyl and Ra being H, alkyl optionally substituted; R=a chain containing up to 10 carbon atoms, optionally comprising one or several heteroatoms, one or several heterocycles; T=H, CH2, CH2CONH2, CH2C≡, (CH2)2NH2; Y=H, OH, halogen; W=H, OH; Z=H or CH3; said products have antifungal properties.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: January 13, 2004
    Assignee: Aventis Pharma S.A.
    Inventors: Olivier Courtin, Patrick Fauveau, Astrid Markus, Dominique Melon Manguer, Jean-Marc Michel, Laurent Schio
  • Publication number: 20030190340
    Abstract: A pharmaceutical preparation comprising a hydrophilic gel-forming agent, water and a compound of the formula I 1
    Type: Application
    Filed: September 18, 1998
    Publication date: October 9, 2003
    Inventors: MANFRED BOHN, KARL THEODOR KRAEMER, ASTRID MARKUS
  • Publication number: 20030187057
    Abstract: The present invention relates to a compound of formula (I) 1
    Type: Application
    Filed: November 8, 2002
    Publication date: October 2, 2003
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Matthias Schiell, Martin Knauf, Luigi Toti, Astrid Markus-Erb
  • Patent number: 6627604
    Abstract: The invention relates to novel peptide derivatives, called memno peptides, of the formula (I): wherein R1, R2, R3, R4, R5, R6, R7, R8 and (A)n have the meaning herein, obtainable by cultivation of Memnoniella echinata FH2272, DSM 13195 or mutants and variants of this, a process for their preparation and the use of the compounds as pharmaceuticals, for example against cardiac insufficiency.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: September 30, 2003
    Assignee: Aventis Pharma Deutschland, GmbH
    Inventors: Laszlo Vertesy, Herbert Kogler, Astrid Markus, Matthias Schiell
  • Patent number: 6599930
    Abstract: The present invention relates to novel active substances (coniosetin and coniosetin derivatives) of the formula I which are produced by the microorganism Coniochaeta ellipsoidea Udagawa (DSM 13856) during fermentation, wherein R, R2, R3, R4, R5, X, X2, X3 and X4 have the meanings stated in the specification, to chemical derivatives of coniosetin, to a process for their preparation and to their use as pharmaceuticals.
    Type: Grant
    Filed: December 6, 2001
    Date of Patent: July 29, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Laszlo Vertesy, Martin Knauf, Astrid Markus-Erb, Luigi Toti, Marie-Cecile Raynal-Wetzel, Florence Fassy
  • Patent number: 6469033
    Abstract: Compounds of the formula I are suitable for the production of pharmaceuticals for the topical treatment of skin infections which are caused by fungi and bacteria.
    Type: Grant
    Filed: August 21, 1998
    Date of Patent: October 22, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Manfred Bohn, Karl Theodor Kraemer, Astrid Markus
  • Publication number: 20020137788
    Abstract: The present invention relates to novel active substances (coniosetin and coniosetin derivatives) of the formula I 1
    Type: Application
    Filed: December 6, 2001
    Publication date: September 26, 2002
    Inventors: Laszlo Vertesy, Martin Knauf, Astrid Markus-Erb, Luigi Toti, Marie Cecile Raynal-Wetzel, Florence Fassy
  • Publication number: 20010031857
    Abstract: The invention relates to novel peptide derivatives, called memno peptides, of the formula (I): 1
    Type: Application
    Filed: February 28, 2001
    Publication date: October 18, 2001
    Inventors: Laszlo Vertesy, Herbert Kogler, Astrid Markus, Matthias Schiell
  • Patent number: 6221844
    Abstract: The invention relates to novel peptides, namely texenomycins, from Scleroderma texense, a process for their preparation and their use as pharmaceuticals, in particular as antimycotics. The texenomycins according to the present invention are distinguished in particular by the amino acid sequence I in which FS is an oxo fatty acid radical, Aib is aminoisobutyric acid and Arg-ol=argininol.
    Type: Grant
    Filed: May 18, 1999
    Date of Patent: April 24, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heike Stump, Wilhelm Stahl, Joachim Wink, Astrid Markus, Herbert Kogler, Jürgen Backhaus
  • Patent number: 6194383
    Abstract: The invention relates to lipopeptides with very homologous amino-acid sequences but different fatty acid residues (lipid portion) which are synthesized by Actinoplanes sp. during fermentation and are released into the culture medium, to a process for isolating the lipopeptides from the culture medium and purifying them, to the use of the lipopeptides as pharmacologically active substances, in particular against Gram-positive bacteria, and to Actinoplanes sp. DSM 7358 for producing the abovementioned lipopeptides.
    Type: Grant
    Filed: March 5, 1997
    Date of Patent: February 27, 2001
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Peter Hammann, Johannes Meiwes, Gerhard Seibert, László Vertesy, Joachim Wink, Astrid Markus
  • Patent number: 6162420
    Abstract: A nail varnish comprising glyceryl triacetate as an active compound and a water-insoluble film-forming agent is suitable for treatment of onychomycoses. If appropriate, the nail varnish can also additionally comprise antimycotic 1-hydroxy-2-pyridone derivatives.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: December 19, 2000
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Manfred Bohn, Karl Theodor Kraemer, Astrid Markus
  • Patent number: 6077830
    Abstract: The present invention relates to bismuth salts of antibiotics of the moenomycin group, processes for their preparation, their use and pharmaceuticals comprising such salts. The salts according to the invention contain antibiotics of the moenomycin group which are so-called phosphoglycolipid antibiotics and which are present individually or as a mixture, or derivatives thereof, and bismuth in defined stoichiometric ratios. They are outstandingly suitable, in particular, for controlling Helicobacter pylori and, thus, for example, for the therapy and prophylaxis of gastric disorders.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: June 20, 2000
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Laszlo Vertesy, Michael Kurz, Astrid Markus, Gerhard Seibert
  • Patent number: 5939399
    Abstract: Novel polyene antibiotics, 3874 H1 to H6, processes for their preparation and use which are suitable for treating fungal diseases, trichomonad diseases, and for treating diseases associated with an increased steroid concentration.
    Type: Grant
    Filed: August 19, 1997
    Date of Patent: August 17, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Laszlo Vertesy, Michael Kurz, Joachim Wink, Astrid Markus, Wilhelm Stahl
  • Patent number: 5405844
    Abstract: Tetracyclic antibiotics and processes for their preparation .beta.-Lactam antibiotics of the formula I, and their pharmaceutically tolerable salts ##STR1## where X is (CH.sub.2).sub.0-2, CR(a)R(b), O, SO.sub.0-2 or NR(c),R1, R2 and R3 are a multiplicity of substituents, are outstanding antibiotics with remarkably good antibacterial activity both against gram-positive and against gram-negative microorganisms. They have a high stability to renal dehydropeptidase.
    Type: Grant
    Filed: May 28, 1992
    Date of Patent: April 11, 1995
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Uwe Gerlach, Rolf Horlein, Norbert Krass, Rudolf Lattrell, Theo Wollmann, Michael Limbert, Astrid Markus