Patents by Inventor Astrid Reiser

Astrid Reiser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining anti-drug antibodies in a minipig sample
    Patent number: 11313864
    Abstract: The present invention relates to in vitro methods for determining the presence or absence of an anti-drug antibody (ADA) or drug/ADA immunecomplexes in a minipig sample. The invention further relates to antibodies specifically binding to minipig IgG that are applicable in the methods of the invention.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: April 26, 2022
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Janis Brockhaus, Astrid Reiser, Mirko Ritter, Kay-Gunnar Stubenrauch, Rudolf Vogel, Markus Zadak
  • METHOD FOR DETERMINING ANTI-DRUG ANTIBODIES IN A MINIPIG SAMPLE
    Publication number: 20200309786
    Abstract: The present invention relates to in vitro methods for determining the presence or absence of an anti-drug antibody (ADA) or drug/ADA immunecomplexes in a minipig sample. The invention further relates to antibodies specifically binding to minipig IgG that are applicable in the methods of the invention.
    Type: Application
    Filed: February 6, 2020
    Publication date: October 1, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Janis BROCKHAUS, Astrid REISER, Mirko RITTER, Kay-Gunnar STUBENRAUCH, Rudolf VOGEL, Markus ZADAK
  • Calibration of High Resolution Melting
    Publication number: 20150315634
    Abstract: The present invention refers to a method and a kit for performing temperature calibration in high resolution melting PCR experiments. The present invention further refers to a method for optimal calibration allowing read-out of identical or similar melting temperatures for target and calibrator. The present invention further refers to an apparatus for performing the method and a computer program for executing the method.
    Type: Application
    Filed: July 6, 2015
    Publication date: November 5, 2015
    Inventors: Astrid Reiser, Gregor Sagner
  • Compositions and methods for detecting methicillin-resistant
    Patent number: 8535888
    Abstract: The present invention relates to methods of detecting the presence or absence of methicillin-resistant S. aureus (MRSA) in a sample, the method comprising performing an amplifying step, a hybridizing step and a detecting step. Furthermore, the present invention relates to primers, probes and kits for the detection of MRSA.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: September 17, 2013
    Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems
    Inventors: Christian Aichinger, Astrid Reiser, James R. Uhl, Franklin R. Cockerill, III
  • Detection of group B
    Patent number: 8097413
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: January 17, 2012
    Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems
    Inventors: James R Uhl, Franklin R Cockerill, III, Christian Aichinger, Astrid Reiser
  • Detection of Group B Streptococcus
    Publication number: 20100291582
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Application
    Filed: July 26, 2010
    Publication date: November 18, 2010
    Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
  • Detection of group B
    Patent number: 7790875
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Grant
    Filed: September 23, 2008
    Date of Patent: September 7, 2010
    Assignees: Mayo Foundation for Medical Education and Research, Roche Molecular Systems, Inc.
    Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
  • Oligonucleotides containing molecular rods
    Patent number: 7541448
    Abstract: The invention is directed to an oligonucleotide comprising a molecular rod, wherein preferentially the molecular rod covalently connects the 3? end of a first nucleotide residue with the 5? end of a second nucleotide residue. Such oligonucleotides are highly advantageous for real time PCR melting curve analysis.
    Type: Grant
    Filed: December 2, 2004
    Date of Patent: June 2, 2009
    Assignee: Roche Diagnostis Operations, Inc.
    Inventors: Dieter Heindl, Astrid Reiser, Karim Tabiti, Martina Junius, Alexander Hauber
  • Detection of Group B Streptococcus
    Publication number: 20090111111
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Application
    Filed: September 23, 2008
    Publication date: April 30, 2009
    Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
  • Detection of group B streptococcus
    Patent number: 7427475
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: September 23, 2008
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: James R. Uhl, Franklin R. Cockerill, III, Christian Aichinger, Astrid Reiser
  • COMPOSITIONS AND METHODS FOR DETECTING METHICILLIN-RESISTANT S. AUREUS
    Publication number: 20080220428
    Abstract: The present invention relates to methods of detecting the presence or absence of methicillin-resistant S. aureus (MRSA) in a sample, the method comprising performing an amplifying step, a hybridizing step and a detecting step. Furthermore, the present invention relates to primers, probes and kits for the detection of MRSA.
    Type: Application
    Filed: December 28, 2007
    Publication date: September 11, 2008
    Inventors: Christian Aichinger, Astrid Reiser, James R. Uhl, Franklin R. Cockerill
  • Oligonucleotides containing molecular rods
    Publication number: 20050142598
    Abstract: The invention is directed to an oligonucleotide comprising a molecular rod, wherein preferentially the molecular rod covalently connects the 3? end of a first nucleotide residue with the 5? end of a second nucleotide residue. Such oligonucleotides are highly advantageous for real time PCR melting curve analysis.
    Type: Application
    Filed: December 2, 2004
    Publication date: June 30, 2005
    Inventors: Dieter Heindl, Astrid Reiser, Karim Tabiti, Martina Junius, Alexander Hauber
  • Detection of group B streptococcus
    Publication number: 20050106578
    Abstract: The invention provides methods to detect group B streptococcus (GBS) in biological samples using real-time PCR. Primers and probes for the detection of GBS are provided by the invention. Articles of manufacture containing such primers and probes for detecting GBS are further provided by the invention.
    Type: Application
    Filed: November 18, 2003
    Publication date: May 19, 2005
    Inventors: James Uhl, Franklin Cockerill, Christian Aichinger, Astrid Reiser
  • Thermostable DNA polymerase from anaerocellum thermophilum
    Publication number: 20050019789
    Abstract: A thermostable enzyme is provided which is derived from the microorganism Anaerocellum thermophilum. The enzyme has a molecular weight of 96 to 100 kDa, shows DNA polymerase activity and reverse transcriptase activity in the presence of magnesium ions. The enzyme may be native or recombinant, and may be used with selected primers and nucleoside triphosphates in a temperature cycling polymerase chain reaction on DNA or RNA as template with or without additional DNA polymerases as an enzyme mixture.
    Type: Application
    Filed: February 2, 2004
    Publication date: January 27, 2005
    Applicant: Roche Diagnostics GMBH
    Inventors: Waltraud Ankenbauer, Gudrun Schmitz-Agheguian, Elizaveta Bonch-Osmolovskaya, Vitaly Svetlichny, Ursula Markau, Bernhard Angerer, Astrid Reiser
  • Thermostable DNA polymerase from anaerocellum thermophilum
    Patent number: 6692932
    Abstract: A thermostable enzyme is provided which is derived from the microorganism Anaerocellum thermophiluml. The enzyme has a molecular weight of 96 to 100 kDa, shows DNA polymerase activity and reverse transcriptase activity in the presence of magnesium ions. The enzyme may be native or recombinant, and may be used with selected primers and nucleoside triphosphates in a temperature cycling polymerase chain reaction on DNA or RNA as template with or without additional DNA polymerases as an enzyme mixture.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: February 17, 2004
    Inventors: Waltraud Ankenbauer, Gudrun Schmitz-Agheguian, Elizaveta Bonch-Osmolovskaya, Vitaly Svetlichny, Ursula Markau, Bernhard Angerer, Astrid Reiser
  • Thermostable DNA polymerase from carboxydothermus hydrogenoformans
    Patent number: 6468775
    Abstract: A DNA polymerase from a thermophilic eubacterium is provided. The DNA polymerase shows magnesium ion dependent reverse transcriptase activity and 3′-5′ exonuclease activity. The invention also includes recombinant plasmids and transformed host cells capable of producing the enzyme. The enzyme is classified into class EC 2.7.7.7., a DNA nucleotidyl transferase DNA-directed type.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: October 22, 2002
    Assignee: Roche Molecular Systems Inc.
    Inventors: Waltraud Ankenbauer, Ursula Markau, Vitaly Svetlichny, Gudrun Schmitz-Agheguian, Astrid Reiser, Bernhard Angerer, Christine Ebenbichler, Frank Laue, Elizaveta Bonch-Osmolovskaya