Patents by Inventor Astrid Zimmermann

Astrid Zimmermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydro-fused pyridines as histone deacetylase inhibitors
    Patent number: 8440830
    Abstract: The compounds of formula (I), wherein ring D and ring E together form a fused ring system selected from formula (II), (III), (IV), (V), (VI), (VII), and the salts of these compounds are novel, effective inhibitors of histone deacetylases.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: May 14, 2013
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Matthias Vennemann, Volker Gekeler, Astrid Zimmermann, Petra Gimmnich, Kamlesh Padiya, Hemant Joshi, Uday Joshi, Mahindra Makhija, Dipak Harel
  • Thiophene-imidazopyridines
    Patent number: 8273890
    Abstract: The invention relates to thiophene-imidazopyridine compounds according to formula (I), wherein the substituents and symbols are as defined in the description. The compounds are inhibitors of PIk1.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: September 25, 2012
    Assignee: 4SC AG
    Inventors: Thomas Stengel, Mathias Schmidt, Steffen Weinbrenner, Alexander Weber, Petra Gimmnich, Volker Gekeler, Thomas Beckers, Astrid Zimmermann, Thomas Maier, Beate Schmidt, Florian Dehmel
  • NOVEL SUBSTITUTED IMIDAZOQUINOLINES
    Publication number: 20110245289
    Abstract: Imidazoquinolines of formula I that contain substituted amine or amide functionality at 1-position and that are effective as Toll like Receptor 7 activators are disclosed. These compounds are useful as anticancer agents.
    Type: Application
    Filed: March 23, 2009
    Publication date: October 6, 2011
    Applicant: 4SC AG
    Inventors: Volker Gekeler, Thomas Maier, Astrid Zimmermann, Hans-Peter Hofmann, Sanjeev Kulkarni, Anil Jagtap, Ganesh Chaure
  • TETRAHYDROBENZOTHIOPHENE DERIVATIVES
    Publication number: 20110044938
    Abstract: Compounds of a certain formula I, in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Application
    Filed: August 15, 2007
    Publication date: February 24, 2011
    Applicant: NYCOMED GMBH
    Inventors: Bjorn Bartels, Mathias Schmidt, Klaus Pekari, Thomas Beckers, Astrid Zimmermann, Volker Gekeler
  • NOVEL TETRAHYDRO-FUSED PYRIDINES AS HISTONE DEACETYLASE INHIBITORS
    Publication number: 20110021494
    Abstract: The compounds of formula (I), wherein ring D and ring E together form a fused ring system selected from formula (II), (III), (IV), (V), (VI), (VII), and the salts of these compounds are novel, effective inhibitors of histone deacetylases.
    Type: Application
    Filed: September 19, 2008
    Publication date: January 27, 2011
    Applicant: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Thomas Baer, Matthias Vennemann, Volker Gekeler, Astrid Zimmermann, Petra Gimmnich, Kamlesh Padiya, Hemant Joshi, Uday Joshi, Mahindra Makhija, Dipak Harel
  • NOVEL TETRAHYDROPYRIDOTHIOPHENES
    Publication number: 20100285149
    Abstract: Compounds of a certain formula I, in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Application
    Filed: August 15, 2007
    Publication date: November 11, 2010
    Inventors: Klaus Pekari, Mathias Schmidt, Astrid Zimmermann, Volker Gekeler, Thomas Beckers, Thomas Bär
  • THIOPHENE-IMIDAZOPYRIDINES
    Publication number: 20100278833
    Abstract: The invention relates to thiophene-imidazopyridine compounds according to formula (I), wherein the substituents and symbols are as defined in the description. The compounds are inhibitors of PIk1.
    Type: Application
    Filed: June 26, 2008
    Publication date: November 4, 2010
    Inventors: Thomas Stengel, Mathias Schmidt, Steffen Weinbrenner, Alexander Weber, Petra Gimmnich, Volker Gekeler, Thomas Beckers, Astrid Zimmermann, Thomas Maier, Beata Schmidt, Florian Dehmel
  • Fused bicyclic pyrimidines
    Patent number: 7776864
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Grant
    Filed: August 14, 2008
    Date of Patent: August 17, 2010
    Assignee: Bayer Schering Pharma AG
    Inventors: Swen Hölder, Matthias Vennemann, Gerrit Beneke, Armin Zülch, Volker Gekeler, Thomas Beckers, Astrid Zimmermann, Hemant Joshi
  • FUSED BICYCLIC PYRIMIDINES
    Publication number: 20100184782
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Application
    Filed: March 25, 2010
    Publication date: July 22, 2010
    Inventors: Swen Hölder, Matthias Vennemann, Gerrit Beneke, Armin Zülch, Volker Gekeler, Thomas Beckers, Astrid Zimmermann, Hemant Joshi
  • BENZOPYRANOPYRAZOLES
    Publication number: 20100104659
    Abstract: Compounds of a certain formula I, in which Ra, Rb and Rc have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: July 12, 2007
    Publication date: April 29, 2010
    Inventors: Matthias Vennemann, Thomas Bär, Thomas Maier, Andreas Lindenmaier, Jürgen Braunger, Markus Boehm, Astrid Zimmermann, Volker Gekeler
  • N-SULPHONYLPYRROLES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS
    Publication number: 20100074862
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Application
    Filed: December 1, 2009
    Publication date: March 25, 2010
    Inventors: Thomas MAIER, Thomas BÄR, Thomas BECKERS, Astrid ZIMMERMANN, Siegfried SCHNEIDER, Volker GEKELER
  • N-sulphonylpyrroles and their use as histone deacetylase inhibitors
    Patent number: 7666868
    Abstract: Compounds of a certain formula (I) in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: February 23, 2010
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Bär, Thomas Beckers, Astrid Zimmermann, Siegfried Schneider, Volker Gekeler
  • INDOLOPYRIDINES AS EG5 KINESIN MODULATORS
    Publication number: 20090246169
    Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: February 21, 2007
    Publication date: October 1, 2009
    Inventors: Matthias Vennemann, Thomas Bar, Jürgen Braunger, Astrid Zimmermann, Volker Gekeler
  • INDOLOPYRIDINES AS EG5 KINESIN MODULATORS
    Publication number: 20090233902
    Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: February 21, 2007
    Publication date: September 17, 2009
    Inventors: Matthias Vennemann, Thomas Bãr, Jürgen Braunger, Astrid Zimmermann, Volker Gekeler
  • FUSED BICYCLIC IMIDAZOLES
    Publication number: 20090156604
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the imidazole to which it is fused, R4, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Application
    Filed: August 14, 2008
    Publication date: June 18, 2009
    Inventors: Swen HOLDER, Armin Zulch, Thomas Bar, Thomas Maier, Astrid Zimmermann, Thomas Beckers, Volker Gekeler, Hemant Joshi, Yogesh Munot, Umesh Bhise, Sunil Chavan, Sachin Shivatare, Sarvesh Patel, Vikas Gore
  • FUSED BICYCLIC PYRIMIDINES
    Publication number: 20090137607
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Application
    Filed: August 14, 2008
    Publication date: May 28, 2009
    Inventors: Swen Holder, Matthias Vennemann, Gerrit Beneke, Armin Zulch, Volker Gekeler, Thomas Beckers, Astrid Zimmermann, Hemant Joshi
  • Sulfonylpyrroles as Histone Deacetylase Inhibitors
    Publication number: 20090117074
    Abstract: The invention relates to compounds of formula (I) which are effective inhibitors of histone deacetylases.
    Type: Application
    Filed: April 7, 2006
    Publication date: May 7, 2009
    Applicant: NYCOMED GmbH
    Inventors: Thomas Maier, Thomas Bar, Thomas Beckers, Astrid Zimmermann, Frank Dullweber, Volker Gekeler
  • N-Sulphonylpyrroles and Their Use as Histone Deacetylase Inhibitors
    Publication number: 20080176848
    Abstract: Compounds of a certain formula (I) in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Application
    Filed: March 14, 2006
    Publication date: July 24, 2008
    Applicant: Nycomed GmbH
    Inventors: Thomas Maier, Thomas Bar, Thomas Beckers, Astrid Zimmermann, Siegfried Schneider, Volker Gekeler