Patents by Inventor Asya Levina

Asya Levina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates of minor groove DNA binders with antisense oligonucleotides
    Patent number: 5955590
    Abstract: Compositions of antisense oligonucleotides conjugated to peptides of a plurality of N-methylpyrrolecarboxamides linked by peptide bonds is provided. The compositions form stable hybridization complexes with DNA and can be used for any purpose which involves hybridizing an oligonucleotide to a DNA molecule, such as in antisense procedures. A method for enhancing oligonucleotide binding to a target is also provided. The method involves the step of hybridizing the target DNA with an oligonucleotide-peptide composition.
    Type: Grant
    Filed: July 15, 1996
    Date of Patent: September 21, 1999
    Assignee: Worcester Foundation for Biomedical Research
    Inventors: Asya Levina, Paul C. Zamecnik