Abstract: A transdermal drug delivery device is disclosed that may comprise a housing including an upper housing portion and a lower housing portion. The lower housing portion may define a bottom surface including skin attachment means for releasably attaching the lower housing portion to skin of a user. The upper housing portion may at least partially surround a central region of the device. The device may also include a microneedle assembly and a reservoir disposed within the central region. The reservoir may be in fluid communication with the microneedle assembly. Additionally, the device may include a pushing element disposed above the microneedle assembly within the central region. The pushing element may be configured to provide a continuous bilateral force having a downward component transmitted through the microneedle assembly and an upward component transmitted through the skin attachment means.

Abstract: Modular crane attachment device for purlins is a crane attachment jig that attaches to the hook of a crane and functions to lift a plurality of purlins in one lift to place each purlin at the precise location on the rafters of a building under construction to allow for immediate attachment of all purlins to the rafters wherein each purlin is fastened into place while held by the crane and modular crane attachment device for purlins, which functions as a giant assembly jig in this manner. Modular crane attachment device for purlins is modular so that it can be broken down by hand into a bundle of 10-20 foot long structural members, fittings, and cables. Modular crane attachment device for purlins is modular so it can be assembled in any length and width to fit any application of any number and any length of purlins required for the building.

Abstract: Systems and methods are disclosed with respect to using a distributed ledger, such as a blockchain, for managing smart vehicle data. The managed data may relate to a detected vehicle event, such as: a motion or position detected by a motion or position sensor as a GPS chip, an accelerometer, a compass, a speedometer, a gyroscope, etc.; braking detected by a braking sensor; turn input detected by a steering wheel sensor; wheel position detected by a wheel sensor; engine temperature detected by a temperature gauge; oil temperature detected by a temperature gauge; a seatbelt status detected by a seatbelt and/or seat sensor; etc.

Abstract: Multiplexed test measurements are conducted using an assay module having a plurality of assay domains. In preferred embodiments, these measurements are conducted in assay modules having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.

Abstract: Drain cleaners are described that include rotatable drums which retain drain cleaning cable. Mounted on the rotatable drum is a motor and optional gearbox for imparting rotation to the drain cleaning cable. The drain cleaners can also include a cable clamp mounted on the rotatable drum. The drain cleaners are configured such that the rotatable drum is free of positional preference regardless of orientation of the drain cleaner.

Abstract: Methods and apparatus to recover unmanned aerial vehicles (UAVs) with kites are disclosed.

Abstract: A system for applying a first coating composition and a second coating composition. The system includes a first high transfer efficiency applicator defining a first nozzle orifice and a second high transfer efficiency applicator defining a second nozzle orifice. The system further includes a substrate defining a target area. The first high transfer efficiency applicator is configured to expel the first coating composition through the first nozzle orifice to the target area of the substrate to form a first coating layer. The second high transfer efficiency applicator is configured to expel the second coating composition through the second nozzle orifice to the first coating layer to form a second coating layer.

Abstract: A device for a medical or cosmetic treatment based on heat is provided. The device includes an impermeable backing layer and an adhesive layer in contact with the backing layer. The device also includes an alkali metal selected from a single, free alkali metal and an alloy alkali metals, the alkali metal in contact with at least a portion of the adhesive layer to define a treatment region. The device also includes a release liner in contact with the adhesive layer and the treatment region. A heat delivery system or kit including the device and a method for its use are also provided.

Abstract: Provided are attenuated strains of M. tuberculosis and M. bovis BCG which are double auxotrophic mutants with genes knocked out in the biosynthetic pathways for arginine and methionine, and compositions and methods of use thereof.

Abstract: Systems and techniques for sharing security data are described herein. Security rules and/or attack data may be automatically shared, investigated, enabled, and/or used by entities. A security rule may be enabled on different entities comprising different computing systems to combat similar security threats and/or attacks. Security rules and/or attack data may be modified to redact sensitive information and/or configured through access controls for sharing.

Abstract: Methods and apparatus to deploy unmanned aerial vehicles (UAVs) by kites are disclosed. An example apparatus to deploy a UAV includes a tether line to support the UAV, a tensioner operatively coupled to the tether line, and a kite operatively coupled to the tether line to support the tether line for deployment of the UAV.

Abstract: An object detection system may include an imager configured to generate image data indicative of an environment in which a machine is present, and a sensor configured to generate sensor data indicative of the environment in which the machine is present. The object detection system may further include an object detection controller including one or more object detection processors configured to receive an image signal indicative of the image data, identify an object associated with the image data, and determine a first location of the object relative to the position of the imager. The one or more object detection processors may also be configured to receive a sensor signal indicative of the sensor data, and determine, based at least in part on the sensor signal, the presence or absence of the object at the first location.

Abstract: A lithographic apparatus that includes an illumination system that conditions a radiation beam, a first stationary plate having a first surface, and a reticle stage defining, along with the first stationary plate, a first chamber. The reticle stage supports a reticle in the first chamber, and the reticle stage includes a first surface spaced apart from a second surface of the first stationary plate, thereby defining a first gap configured to suppress an amount of contamination passing from a second chamber to the first chamber. The first stationary plate is between the reticle stage and both the illumination system and a projection system configured to project a pattern imparted to the radiation beam by the patterning device onto a substrate.

Abstract: A surgical clip applier includes a handle assembly and an elongated assembly configured to releasably engage the handle assembly. The handle assembly includes a trigger and a drive bar wherein pivoting of the trigger through a full actuation stroke translates the drive bar through a full drive distance. The drive bar has a magnetic distal end portion. The elongated assembly includes an inner drive assembly including a magnetic proximal end portion. Upon engagement of the elongated assembly with the handle assembly, the magnetic proximal end portion of the inner drive assembly is configured to attract the magnetic distal end portion of the drive bar to move the drive bar and pivot the trigger such that the trigger is pivotable through a reduced actuation stroke to translate the drive bar through a reduced drive distance.

Abstract: A material deposition system comprises a dopant source containing at least one dopant precursor material, an inert gas source containing at least one noble gas, and a physical vapor deposition apparatus in selective fluid communication with the dopant source and the inert gas source. The physical vapor deposition apparatus comprises a housing structure, a target electrode, and a substrate holder. The housing structure is configured and positioned to receive at least one feed fluid stream comprising the at least one dopant precursor material and the at least one noble gas. The target electrode is within the housing structure and is in electrical communication with a signal generator. The substrate holder is within the housing structure and is spaced apart from the target electrode. A method of forming a microelectronic device, a microelectronic device, a memory device, and an electronic system are also described.

Abstract: Powered chairs, assemblies for use in the powered chairs, and components for use in the assemblies are provided. Electrical systems for use in the powered chairs, and components for use in the electrical systems are provided. Control systems and methods for operating powered chairs are also provided. Any given chair may be locally and/or remotely controlled.

Abstract: A cloud capacity system enables calculation and tracking of cloud capacity metrics for data center pods. The system includes a “Cloud Capacity Snapshot” table having a number of different cloud capacity columns; a “Cloud Capacity Query” table that stores a respective, customizable query for each of the cloud capacity columns defining criteria for selecting and combining data to calculate the corresponding cloud capacity metric value; and a “Cloud Capacity URLs” table that stores cloud capacity universal resource locator (URLs). Each cloud capacity URL embodies or encodes a respective cloud capacity query of the “Cloud Capacity Query” table for a given combination of a particular cloud capacity column and a particular pod in the “Cloud Capacity Snapshot” table. As such, by executing the queries encoded in the “Cloud Capacity URLs” table, each cloud capacity field of the “Cloud Capacity Snapshot” table is populated with the corresponding cloud capacity metric value.

Abstract: An intraluminal ultrasound imaging device includes a flexible elongate member configured to be inserted into a body lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion. The device also includes an ultrasound scanner assembly disposed at the distal portion of the flexible elongate member. The ultrasound scanner assembly includes a flexible substrate; a transducer region positioned on the flexible substrate; and a control region positioned on the flexible substrate, wherein the transducer region and the control region are radially arranged relative to one another. Associated devices, systems, and methods are also described.

Abstract: A rail and/or anchor system and method for transjugular intrahepatic portosystemic shunt procedures. The system includes a rail and/or anchor line anchorable to surrounding tissue or used as a rail, and configured to guide the displacement of at least one of a needle and an outer sheath. The rail and/or anchor line may include a balloon catheter, and a balloon of the balloon catheter may be configured to selectively anchor the anchor line to surrounding tissue by the balloon being inflated, and unanchor the anchor line to surrounding tissue by the balloon being deflated. The balloon catheter can be stiff so that it can be used as a rail even when not anchored. The balloon catheter may be configured for executing wedge venography, and for measuring pressure at a tip of the balloon catheter while a balloon of the balloon catheter is inflated. The anchor line may include one or more hooks for anchoring the anchor line to surrounding tissue. The one or more hooks may be selectively advanceable and retractable.

Abstract: An air data probe includes a probe body including a probe wall. The probe body is formed from a first material by direct energy metal deposition. An insert is positioned in the probe wall. The insert is formed from a second material different from the first material. The insert is encapsulated in the probe wall via the direct energy metal deposition. A method of forming an air data probe includes forming one or more thermally conductive inserts, and encapsulating the one or more inserts into a wall of an air data probe via direct energy metal deposition. The air data probe is formed from a first material and the one or more inserts are formed from a second material different from the first material.