Patents by Inventor Athanasios I. Zavras

Athanasios I. Zavras has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETIC RISK ASSESSMENT TECHNOLOGY FOR EPITHELIAL CANCER INVOLVING GENE-ENVIRONMENT INTERACTION BETWEEN ERCC5 AND TOBACCO USE
    Publication number: 20120058486
    Abstract: Methods and compositions for assessing ERCC5 gene expression in view of certain environmental exposures and determining the risk of an individual for developing one or more epithelial cancers are provided.
    Type: Application
    Filed: November 11, 2011
    Publication date: March 8, 2012
    Applicant: President and Fellows of Harvard College
    Inventor: Athanasios I. Zavras
  • Genetic risk assessment technology for epithelial cancer involving gene-environment interaction between ERCC5 and tobacco use
    Patent number: 8084205
    Abstract: Methods and compositions for assessing ERCC5 gene expression in view of certain environmental exposures and determining the risk of an individual for developing one or more epithelial cancers are provided.
    Type: Grant
    Filed: January 7, 2009
    Date of Patent: December 27, 2011
    Assignee: President and Fellows of Harvard College
    Inventor: Athanasios I. Zavras
  • Clinical Method for Individualized Epithelial Cancer Screening Involving ERCC5 and IGF2R Genetic Testing and Gene-Environment Interactions
    Publication number: 20110269142
    Abstract: A system for determining individualized risk of developing aerodigestive cancers or cancers of the liver is described. Methods and compositions for assessing ERCC5 and/or IGF2R genetic variation and expression and their effects in view of certain environmental exposures in determining the risk of an individual for developing one or more epithelial cancers are provided. The system includes a kit used to collect a DNA sample from an individual and data related to the individual's medical and occupational history, use of tobacco and alcohol products as well as the individual's environment. An algorithm may be applied to transform the DNA sample and data into an individualized risk score, accounting for inter-individual variation in genetic profile and environmental/lifestyle exposures. The risk score may be indicative of the individual's risk of having or developing epithelial cancer, and the cancers prognosis. The risk score may be distributed to one or more of the individual, physician and other personnel.
    Type: Application
    Filed: April 30, 2010
    Publication date: November 3, 2011
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventor: Athanasios I. Zavras
  • GENETIC RISK ASSESSMENT TECHNOLOGY FOR EPITHELIAL CANCER INVOLVING GENE-ENVIRONMENT INTERACTION BETWEEN ERCC5 AND TOBACCO USE
    Publication number: 20090253136
    Abstract: Methods and compositions for assessing ERCC5 gene expression in view of certain environmental exposures and determining the risk of an individual for developing one or more epithelial cancers are provided.
    Type: Application
    Filed: January 7, 2009
    Publication date: October 8, 2009
    Applicant: President and Fellows of Harvard College
    Inventor: Athanasios I. Zavras