Patents by Inventor Athanasios Yotakis

Athanasios Yotakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphinic pseudo-peptides that may be used as matrix zinc metalloprotease inhibitors
    Patent number: 6630501
    Abstract: The invention relates to pseudo-peptides according to the formula: wherein R1 is a group inhibiting an amine function, or an amino acid residue or peptide with an inhibited terminal amino function, R2 represents the lateral chain of a natural or non-natural amino acid, R3 represents: 1) the lateral chain of a natural amino acid except for Gly and Ala, not substituted or substituted by an aryl group, 2) an aralkyl group, or 3) an alkyl group comprising at least 3 carbon atoms, and R4 represents a lateral chain of natural or non-natural amino acid. They are useful as matrix zinc metalloprotease inhibitors, particularly in the treatment of cancer.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: October 7, 2003
    Assignees: Commissariat a l'energie Atomique, Institut National de la Recherche Medical, Centre National de la Recherche Scientifique
    Inventors: Vincent Dive, Philippe Cuniasse, Marie-Christine Rio, Paul Basset, Athanasios Yotakis, Fabrice Beau, Stamania Vassiliou