Patents by Inventor Athena Nagi

Athena Nagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Buffer formulations for enhanced antibody stability
    Patent number: 10376582
    Abstract: The invention provides buffered formulations of adalimumab. The formulations comprise a buffer comprising an acetate salt, mannitol, glacial acetic acid, sodium chloride, and polysorbate 80. The formulations have an acidic pH, and enhance the thermal, conformational and colloidal stability of antibodies, including the adalimumab antibody.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: August 13, 2019
    Assignee: Outlook Therapeutics, Inc.
    Inventors: John Cini, Athena Nagi, Maria Taddei
  • Buffer Formulations for Enhanced Antibody Stability
    Publication number: 20160235845
    Abstract: The invention provides buffered formulations of adalimumab. The formulations comprise a buffer comprising an acetate salt, mannitol, glacial acetic acid, sodium chloride, and polysorbate 80. The formulations have an acidic pH, and enhance the thermal, conformational and colloidal stability of antibodies, including the adalimumab antibody.
    Type: Application
    Filed: October 16, 2014
    Publication date: August 18, 2016
    Inventors: John Cini, Athena Nagi, Maria Taddei
  • Methods and compositions for preventing oxidative degradation of proteins
    Publication number: 20050276823
    Abstract: Methods and compositions for preventing oxidative damage to proteins, particularly antibodies, are provided. The compositions include a combination of metal chelators, such as DTPA, EGTA, and/or DEF, and can further include one or more free radical scavengers, particularly scavengers of oxygen radicals. Methods for enhancing protein stability using the compositions of the invention are also disclosed.
    Type: Application
    Filed: July 11, 2003
    Publication date: December 15, 2005
    Inventors: John Cini, Athena Nagi