Abstract: The disclosure relates to a method for determining a boundary about an area of interest in an image set. The includes obtaining the image set from an imaging modality and processing the image set in a convolutional neural network. The convolutional neural network is trained to perform the acts of predicting an inverse distance map for the actual boundary in the image set; and deriving the boundary from the inverse distance map. The disclosure also relates to a method of training a convolutional neural network for use in such a method, and a medical imaging arrangement.

Abstract: Systems and methods for generating a segmentation mask of an anatomical structure, along with a measure of uncertainty of the segmentation mask, are provided. In accordance with one or more embodiments, a plurality of candidate segmentation masks of an anatomical structure is generated from an input medical image using one or more trained machine learning networks. A final segmentation mask of the anatomical structure is determined based on the plurality of candidate segmentation masks. A measure of uncertainty associated with the final segmentation mask is determined based on the plurality of candidate segmentation masks. The final segmentation mask and/or the measure of uncertainty are output.

Abstract: For segmentation in medical imaging, a shape generative adversarial network (shape GAN) is used in training. By including shape information in a lower dimensional space than the pixels or voxels of the image space, the network may be trained with a shape loss or optimization. The adversarial loss and the shape loss are used to train the network, so the resulting generator may segment complex shapes in 2D or 3D. Other optimization may be used, such as using a loss in image space.

Abstract: The disclosure relates to a method for determining a boundary about an area of interest in an image set. The includes obtaining the image set from an imaging modality and processing the image set in a convolutional neural network. The convolutional neural network is trained to perform the acts of predicting an inverse distance map for the actual boundary in the image set; and deriving the boundary from the inverse distance map. The disclosure also relates to a method of training a convolutional neural network for use in such a method, and a medical imaging arrangement.

Abstract: Systems and methods for generating a segmentation mask of an anatomical structure, along with a measure of uncertainty of the segmentation mask, are provided. In accordance with one or more embodiments, a plurality of candidate segmentation masks of an anatomical structure is generated from an input medical image using one or more trained machine learning networks. A final segmentation mask of the anatomical structure is determined based on the plurality of candidate segmentation masks. A measure of uncertainty associated with the final segmentation mask is determined based on the plurality of candidate segmentation masks. The final segmentation mask and/or the measure of uncertainty are output.

Abstract: For segmentation in medical imaging, a shape generative adversarial network (shape GAN) is used in training. By including shape information in a lower dimensional space than the pixels or voxels of the image space, the network may be trained with a shape loss or optimization. The adversarial loss and the shape loss are used to train the network, so the resulting generator may segment complex shapes in 2D or 3D. Other optimization may be used, such as using a loss in image space.