Abstract: An objective of the present invention is to provide methods for promoting antigen uptake into cells by antigen-binding molecules, methods for increasing the number of times of antigen binding by one antigen-binding molecule, methods for promoting reduction of the antigen concentration in plasma by administering antigen-binding molecules, and methods for improving the plasma retention of an antigen-binding molecule, as well as antigen-binding molecules that allow enhanced antigen uptake into cells, antigen-binding molecules having an increased number of times of antigen binding, antigen-binding molecules that can promote reduction of the antigen concentration in plasma when administered, antigen-binding molecules with improved plasma retention, pharmaceutical compositions comprising the above antigen-binding molecules, and methods for producing them. The present inventors revealed that the above objective can be achieved by using antigen-binding molecules that show calcium-dependent antigen-antibody reaction.

Abstract: A stator coil for a rotating electrical machine, the stator coil including a stator iron core and a coil formed by winding an enamel wire around a slot of the stator iron core, in which the enamel wire is covered with a cured product of a first insulating varnish containing a polyester resin and the coil is covered with a cured product of a second insulating varnish containing an epoxy acrylate resin. The stator coil for a rotating electrical machine has an insulating layer with excellent adhesive strength to prevent thermal degradation of its enamel wire and has excellent dielectric strength properties retained for an extended period of time.