Patents by Inventor Atsuhiko Machida

Atsuhiko Machida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis B vaccine
    Patent number: 5019386
    Abstract: A polypetide vaccine is disclosed with the amino acid sequence of Asp-Pro-Arg-Val-Arg-Gly-Leu-Try-Phe-Pro-Ala-Gly-Gly-Ser-Ser-Ser-Gly-Thr-Va l that bears the receptor for polymerized human serum albumin capable of raising antibodies to inhibit the access and entry of hepatitis B virus (HBV) to hepatocytes. The polypeptide vaccine is also shown in which the 9th amino acid residue (Phe) is replaced by leucine. In addition, there is disclosed hepatitis B polypeptide vaccine P31 which is capable of raising antibodies to block the attachment of HBV to hepatocytes.
    Type: Grant
    Filed: August 29, 1988
    Date of Patent: May 28, 1991
    Assignee: Institute of Immunology Co., Ltd.
    Inventors: Atsuhiko Machida, Tetsuo Nakamura