Patents by Inventor Atsuhiro IIMURO

Atsuhiro IIMURO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
    Publication number: 20230128162
    Abstract: The present invention provides a compound exhibiting coronavirus 3CL protease inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. Furthermore, the present invention provides a crystalline form useful as an active pharmaceutical ingredient, and a pharmaceutical composition comprising the same. A compound represented by Formula (I): wherein Y is N or the like; R1 is substituted or unsubstituted aromatic heterocyclyl or the like; R2 is substituted or unsubstituted aromatic carbocyclyl or the like; R3 is substituted or unsubstituted aromatic heterocyclyl or the like; —X— is —NH— or the like; m is 1 or the like; R5a is each independently a hydrogen atom or the like; R5b is each independently a hydrogen atom or the like; n is 1 or the like; R4a is each independently a hydrogen atom or the like; and R4b is each independently a hydrogen atom or the like, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 17, 2022
    Publication date: April 27, 2023
    Applicants: Shionogi & Co., Ltd., NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Yuki TACHIBANA, Shota UEHARA, Yuto UNOH, Kenji NAKAHARA, Yoshiyuki TAODA, Koji KASAMATSU, Yukiko YAMATSU, Shigeru ANDO, Atsuhiro IIMURO, Takahiro SUTO, Michihito SASAKI
  • Method for producing optically active 2-arylpiperidinium salt
    Patent number: 9012649
    Abstract: Disclosed is a method for producing an optically active 2-arylpiperidinium salt, comprising asymmetrically hydrogenating a pyridinium salt in the presence of an iridium complex and hydrogen, the 2-arylpiperidinium salt being represented by the following general formula (1): wherein R1, R2, X, *, and m are as described in Description, the pyridinium salt being represented by the following general formula (2): wherein R1, R2, X, and m are as described in Description, and the iridium complex being represented by the following general formula (3): IrH(Z)(Q)(PP*)??(3), wherein Z, PP*, and Q are as described in Description, or the following general formula (4): [{IrH(PP*)}2(?-Z)3]Z??(4), wherein Z and PP* are as described in Description.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: April 21, 2015
    Assignee: Takasago International Corporation
    Inventors: Kazushi Mashima, Yusuke Kita, Takuto Nagano, Atsuhiro Iimuro, Kenta Yamaji, Shoji Hida, Kiyoto Hori, Hideki Nara
  • METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERIDINIUM SALT
    Publication number: 20140213792
    Abstract: Disclosed is a method for producing an optically active 2-arylpiperidinium salt, comprising asymmetrically hydrogenating a pyridinium salt in the presence of an iridium complex and hydrogen, the 2-arylpiperidinium salt being represented by the following general formula (1): wherein R1, R2, X, *, and m are as described in Description, the pyridinium salt being represented by the following general formula (2): wherein R1, R2, X, and m are as described in Description, and the iridium complex being represented by the following general formula (3): IrH(Z)(Q)(PP*)??(3), wherein Z, PP*, and Q are as described in Description, or the following general formula (4): [{IrH(PP*)}2(?-Z)3]Z??(4), wherein Z and PP* are as described in Description.
    Type: Application
    Filed: January 30, 2014
    Publication date: July 31, 2014
    Applicant: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Kazushi MASHIMA, Yusuke KITA, Takuto NAGANO, Atsuhiro IIMURO, Kenta YAMAJI, Shoji HIDA, Kiyoto HORI, Hideki NARA