Patents by Inventor Atsunobu Hiraoka

Atsunobu Hiraoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hematopoietic stem cell growth factor (SCGF)
    Patent number: 6541217
    Abstract: The present invention provides a novel polypeptide possessing growth activities on hematopoietic stem cells, a gene encoding the polypeptide and an antibody reacting specifically with the polypeptide, as well as a method for isolating the above gene and a vector for use in the method. According to the present invention, it is possible to elucidate the pathogenesis of various hematopoietic diseases due to abnormalities in hematopoietic stem cells and of bone marrow inhibition, and to diagnose and treat such diseases. According to the present invention, it is also possible to amplify hematopoietic stem cells in vitro for bone marrow transplantation necessary for the treatment of such diseases or improve efficiency of a gene transfer into hematopoietic stem cells for utilizing the gene therapy. The vector and the method of gene isolation developed to isolate the SCGF gene of the invention are applicable to search for other novel genes and able to contribute to the technological progress in genetic engineering.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: April 1, 2003
    Assignees: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Atsunobu Hiraoka, Atsushi Sugimura, Hiroyuki Mio
  • HEMATOPOIETIC STEM CELL GROWTH FACTOR (SCGF)
    Publication number: 20020099196
    Abstract: The present invention provides a novel polypeptide possessing growth activities on hematopoietic stem cells, a gene encoding the polypeptide and an antibody reacting specifically with the polypeptide, as well as a method for isolating the above gene and a vector for use in the method. According to the present invention, it is possible to elucidate the pathogenesis of various hematopoietic diseases due to abnormalities in hematopoietic stem cells and of bone marrow inhibition, and to diagnose and treat such diseases. According to the present invention, it is also possible to amplify hematopoietic stem cells in vitro for bone marrow transplantation necessary for the treatment of such diseases or improve efficiency of a gene transfer into hematopoietic stem cells for utilizing the gene therapy. The vector and the method of gene isolation developed to isolate the SCGF gene of the invention are applicable to search for other novel genes and able to contribute to the technological progress in genetic engineering.
    Type: Application
    Filed: April 27, 1998
    Publication date: July 25, 2002
    Applicant: KYOWA HAKKO KOGYO CO., LTD. AND ATSUNOBU HIRAOKA
    Inventors: ATSUNOBU HIRAOKA, ATSUSHI SUGIMURA, HIROYUKI MIO