Abstract: In the COP treatment and the SOP treatment of the interior of a chamber of an aseptic filler, any cleaning liquid or aseptic water remaining in the chamber is quickly removed before spray of a sterilizer containing peracetic acid or hydrogen peroxide. A transfer device for transferring a container in the chamber of the aseptic filler is driven to remove the cleaning liquid sued for the COP treatment or the aseptic water used for the SOP treatment.

Abstract: To provide a therapeutic agent for cancer having a higher therapeutic effect. A therapeutic agent for cancer, containing: at least one selected from the group consisting of curcumin and a derivative thereof; and at least one selected from the group consisting of an anti-PD-1 antibody, an anti-PD-L1 antibody, and an anti-PD-L2 antibody in combination.

Abstract: A content-filling system (10) includes a water sterilization line (50) that sterilizes water without heating, an undiluted-solution sterilization line (70) that heats and sterilizes a product undiluted solution, and a filling device (20) that is connected to the water sterilization line (50) and the undiluted-solution sterilization line (70) and that fills the water and the product undiluted solution in bottles (100).

Abstract: A beverage filling system for filling a container with a carbonated beverage includes beverage supply piping that supplies the carbonated beverage, a beverage filling machine that is coupled to the beverage supply piping, and a controller that controls the beverage filling system. The beverage filling machine includes a filling nozzle and a beverage supply line, a counter gas line, and a snift line each of which is coupled to the filling nozzle. The controller causes a first piping channel including the beverage supply line to be performed CIP processing, and causes a second piping channel including the counter gas line to be performed CIP processing.

Abstract: A beverage filling system for filling a container with a beverage includes: beverage supply piping that supplies the beverage; a beverage filling machine that is coupled to the beverage supply piping; CIP circulation piping that is coupled to the beverage filling machine, that feeds a cleaning liquid flowed out from the beverage filling machine during CIP processing toward the beverage supply piping, and that circulates the cleaning liquid; and a controller that controls the beverage filling system. A heater that heats the cleaning liquid that flows through the CIP circulation piping and a holding tube through which the cleaning liquid heated by the heater passes are provided in the CIP circulation piping. The cleaning liquid heated by the heater is set in such a way as to pass through the holding tube while spending a predetermined residence time or longer.

Abstract: A cap sterilization device (50) includes a sterilant spraying chamber (52) in which a sterilant is sprayed onto a cap (33) and an air-rinsing chamber (53) in which the cap (33) onto which the sterilant has been sprayed in the sterilant spraying chamber (52) is subjected to air-rinsing. A sterilant spraying wheel (74) that conveys the cap (33) while rotating the cap (33) is disposed in the sterilant spraying chamber (52). An air-rinsing wheel (75) that conveys the cap (33) onto which the sterilant has been sprayed while rotating the cap (33) is disposed in the air-rinsing chamber (53). The air-rinsing chamber (53) is disposed vertically above the sterilant spraying chamber (52).

Abstract: A filling valve that has a high temperature due to an SIP is cooled in a short time. An aseptic water is blasted to an outer surface of the filling valve.

Abstract: A document scanner includes a casing and a document cover disposed above the casing. The casing includes a document glass and houses an image scanner. The document cover has one end portion and the other end portion opposite to the first end portion in a first direction and is configured to pivotally move about the one end portion between a closed position in which the other end portion covers the document glass and an open position in which the other end portion uncovers the document glass. The other end portion has an end surface that intersects, when the document cover is at the closed position, with an upper surface of the document glass. The end surface has an indication indicating a location to which an external device is to be brought into proximity to establish short-range wireless communication between the document scanner and the external device.

Abstract: A device capable of stably obtaining gas of a sterilizer containing hydrogen peroxide for a long time is provided. A cleaning device that cleans a heating surface that gasifies a sterilizer of a gasifier for a sterilizer is provided, and after an operation for a fixed time period, the heating surface is cleaned.

Abstract: A water sterilizer (60) includes a foreign-material removal filter (61) that removes foreign material in water, a first sterilizer (62) that is disposed downstream of the foreign-material removal filter (61), a first sterile filter (63) that is disposed downstream of the first sterilizer (62), a second sterilizer (64) that is disposed downstream of the first sterile filter (63), and a second sterile filter (65) that is disposed downstream of the second sterilizer (64). The first sterilizer (62) and the second sterilizer (64) sterilize the water by using an ultraviolet ray.

Abstract: In the COP treatment and the SOP treatment of the interior of a chamber of an aseptic filler, any cleaning liquid or aseptic water remaining in the chamber is quickly removed before spray of a sterilizer containing peracetic acid or hydrogen peroxide. A transfer device for transferring a container in the chamber of the aseptic filler is driven to remove the cleaning liquid sued for the COP treatment or the aseptic water used for the SOP treatment.

Abstract: A carbonated beverage aseptic filling system (10) comprises: a filling nozzle (72) for filling a carbonated beverage; a carbonated beverage filling tank (75) connected to the filling nozzle (72) via a carbonated beverage supplying pipe (73) and a counter pressure pipe (74); a snift pipe (78) connected to the filling nozzle; and an aseptic chamber (13) enclosing the filling nozzle (72), at least part of the carbonated beverage supplying pipe (73), and at least part of the counter pressure pipe (74). The carbonated beverage supplying pipe (73) and the counter pressure pipe (74) are attached to the aseptic chamber (13) by a rotary joint (77). A discharging valve (79) is provided in the snift pipe (78) inside the aseptic chamber (13), and gas from the snift pipe (78) is discharged into the aseptic chamber.

Abstract: A document scanner includes a casing and a document cover disposed above the casing. The casing includes a document glass and houses an image scanner. The document cover has one end portion and the other end portion opposite to the first end portion in a first direction and is configured to pivotally move about the one end portion between a closed position in which the other end portion covers the document glass and an open position in which the other end portion uncovers the document glass. The other end portion has an end surface that intersects, when the document cover is at the closed position, with an upper surface of the document glass. The end surface has an indication indicating a location to which an external device is to be brought into proximity to establish short-range wireless communication between the document scanner and the external device.

Abstract: In an aseptic filling machine including content supply piping for feeding a content to a filler via a heat sterilization portion, CIP and SIP of the inside of the content supply piping is performed by circulating a cleaning liquid, SIP is performed by heating the cleaning liquid to a required temperature for sterilization from the start of the CIP or during the CIP, the overall heat transfer coefficient of the heating piping is calculated, it is determined that the CIP is completed when the overall heat transfer coefficient calculated reaches a target value, temperatures are measured by a plurality of temperature sensors provided, a lowest temperature is selected from the measured temperatures, F values are calculated for the selected lowest temperature, the calculated F values are accumulated, and it is determined that the SIP is completed when the accumulated F value reaches a target value.

Abstract: A device capable of stably obtaining gas of a sterilizer containing hydrogen peroxide for a long time is provided. A cleaning device that cleans a heating surface that gasifies a sterilizer of a gasifier for a sterilizer is provided, and after an operation for a fixed time period, the heating surface is cleaned.

Abstract: In an aseptic filling apparatus, a CIP of the content filling station is performed after rotation of a wheel in the content filling station is stopped, a COP or SOP of the content filling station is performed while the wheel in the content filling station is rotating immediately after the CIP is completed, an SIP of the content filling station is performed with rotation of the wheel in the content filling station being stopped immediately after the COP or SOP is completed, and one or both of the COP and SOP of the other stations is performed in a predetermined order while wheels in the other stations are rotating in a period from the start of the CIP to the end of the SIP.

Abstract: In an aseptic filling apparatus, a CIP of the content filling station is performed after rotation of a wheel in the content filling station is stopped, a COP or SOP of the content filling station is performed while the wheel in the content filling station is rotating immediately after the CIP is completed, an SIP of the content filling station is performed with rotation of the wheel in the content filling station being stopped immediately after the COP or SOP is completed, and one or both of the COP and SOP of the other stations is performed in a predetermined order while wheels in the other stations are rotating in a period from the start of the CIP to the end of the SIP.

Abstract: In an aseptic filling apparatus, a CIP of the content filling station is performed after rotation of a wheel in the content filling station is stopped, a COP or SOP of the content filling station is performed while the wheel in the content filling station is rotating immediately after the CIP is completed, an SIP of the content filling station is performed with rotation of the wheel in the content filling station being stopped immediately after the COP or SOP is completed, and one or both of the COP and SOP of the other stations is performed in a predetermined order while wheels in the other stations are rotating in a period from the start of the CIP to the end of the SIP.

Abstract: A method of cleaning and sterilizing a drink filling apparatus that includes drink supply piping that feeds a drink sterilized in a heating sterilization part into a filling machine includes performing a cleaning in place (CIP), in which a cleaner is circulated in the drink supply piping to remove a drink residue or the like on an interior of the drink supply piping, raising a temperature of the cleaner to a temperature required for a sterilizing in place (SIP), which is performed in succession to the CIP to sterilize the interior of the drink supply piping, from an early stage or middle stage of the CIP, then performing the SIP for the interior of the drink supply piping, and washing the cleaner away with aseptic water heated and sterilized in the heating sterilization part.

Abstract: Only a bottle properly preliminarily heated is sterilized by hydrogen peroxide. Temperature inspection to the bottle is performed while travelling the bottle. During the inspection, a bottle of which temperature does not reach a predetermined temperature is removed and a bottle of which temperature reaches the predetermined temperature is continuously travelled, hydrogen peroxide condensed mist ? is blown toward a mouth portion 1a of the bottle by a spray tube 59 disposed at a predetermined position, and hot air is blown into the bottle from the nozzle while the nozzle 64 following the mouth portion of the bottle. According to such operation, only the bottle properly heated can be sterilized by the hydrogen peroxide, Thereafter, beverage fills the bottle, which is then sealed.