Patents by Inventor Atsushi Kittaka

Atsushi Kittaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VDR-silent vitamin D derivative as inhibitors of SREBP and pharmaceutical use thereof
    Patent number: 11932595
    Abstract: Provided are vitamin D3 derivatives of formula (I), pharmaceutical compositions thereof, and pharmaceutical or medical uses thereof for treating metabolic disease, a liver disease, obesity, diabetes, cardiovascular disease, or cancer in a patient in need thereof.
    Type: Grant
    Filed: September 17, 2021
    Date of Patent: March 19, 2024
    Assignee: KYOTO UNIVERSITY, NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY, TEIKYO UNIVERSITY and THE UNIVERSITY OF TOKYO
    Inventors: Motonari Uesugi, Yasushi Takemoto, Kazuo Nagasawa, Atsushi Kittaka, Fumihiro Kawagoe, Hayato Nakagawa
  • VDR-SILENT VITAMIN D DERIVATIVE AS INHIBITORS OF SREBP AND PHARMACEUTICAL USE THEREOF
    Publication number: 20220081381
    Abstract: Provided are vitamin D3 derivatives of formula (I), pharmaceutical compositions thereof, and pharmaceutical or medical uses thereof for treating metabolic disease, a liver disease, obesity, diabetes, cardiovascular disease, or cancer in a patient in need thereof.
    Type: Application
    Filed: September 17, 2021
    Publication date: March 17, 2022
    Inventors: Motonari Uesugi, Yasushi Takemoto, Kazuo Nagasawa, Atsushi Kittaka, Fumihiro Kawagoe, Hayato Nakagawa, Adil Salih Wakil
  • Vitamin Dlactone derivatives
    Patent number: 9073885
    Abstract: A compound represented by the following Formula (1) that is effective for the treatment of Paget's disease of bone or hypercalcemia or a medically acceptable solvate thereof; [wherein R1 refers to hydrogen atom, C1-C6 alkyl group optionally substituted with hydrogen group or C1-C6 alkoxy group optionally substituted with hydroxyl group, R2a and R2b refer to hydrogen atom, C1-C10 alkyl group optionally substituted with hydroxyl group, C6-C10 aryl group optionally substituted with hydroxyl group or C7-C12 aralkyl group optionally substituted with a hydroxyl group, or are combined to represent ethylene group. However, a compound in which R1 is a hydrogen atom or a methyl group and R2a and R2b are hydrogen atoms is excluded].
    Type: Grant
    Filed: January 29, 2004
    Date of Patent: July 7, 2015
    Assignee: Teijin Pharma Limited
    Inventors: Kazuya Takenouchi, Miyuki Anzai, Hiroshi Saito, Kazuhisa Okada, Seiichi Ishizuka, Daishiro Miura, Hiroaki Takayama, Atsushi Kittaka, Nozomi Saito, Toshie Fujishima
  • VITAMIN D3 LACTAM DERIVATIVE
    Publication number: 20110207944
    Abstract: Compound represented by formula (1) or a pharmaceutically acceptable solvate thereof, useful for treating or preventing Paget's disease of bone, hypercalcaemia, osteoporosis or asthma. (1) R1 represents a C1-C6 alkyl group or C7-C15 aralkyl group (the aromatic ring of which can be substituted by a C1-C6 alkyl group, C1-C6 alkoxy group, a hydroxyl group, a halogenatom or a trifluoromethyl group), R2 represents a C1-C6 alkyl group, and R3 represents a C1-C6 alkyl or alkoxy group, which can be substituted with a hydroxyl group.
    Type: Application
    Filed: November 2, 2009
    Publication date: August 25, 2011
    Applicant: TEIJIN PHARMA LIMITED
    Inventors: Yuko Nakamura, Hiroshi Saito, Kazuo Nagasawa, Atsushi Kittaka
  • 2-SUBSTITUTED VITAMIN D DERIVATIVES
    Publication number: 20090124819
    Abstract: The object of the present invention is to synthesize novel vitamin D derivatives. According to the present invention, there are provided vitamin D derivatives represented by the following general formula (1): wherein R1 and R2 may be the same or different, and each represents a straight chain or branched chain alkyl group optionally substituted by a hydroxyl group, and R3 represents a straight chain or branched chain alkyl group optionally substituted by a hydroxyl group.
    Type: Application
    Filed: January 7, 2009
    Publication date: May 14, 2009
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Hiroaki Takayama, Toshie Fujishima, Atsushi kittaka
  • Vitamin d3 lactone derivatives
    Publication number: 20060148768
    Abstract: A compound represented by the following Formula (1) that is effective for the treatment of Paget's disease of bone or hypercalcemia or a medically acceptable solvate thereof; [wherein R1 refers to hydrogen atom, C1-C6 alkyl group optionally substituted with hydrogen group or C1-C6 alkoxy group optionally substituted with hydroxyl group, R2a and R2b refer to hydrogen atom, C1-C10 alkyl group optionally substituted with hydroxyl group, C6-C10 aryl group optionally substituted with hydroxyl group or C7-C12 aralkyl group optionally substituted with a hydroxyl group, or are combined to represent ethylene group. However, a compound in which R1 is a hydrogen atom or a methyl group and R2a and R2b are hydrogen atoms is excluded].
    Type: Application
    Filed: January 29, 2004
    Publication date: July 6, 2006
    Inventors: Kazuya Takenouchi, Miyuki Anzai, Hiroshi Saito, Kazuhisa Okada, Seiichi Ishizuka, Daishiro Miura, Hiroaki Takayama, Atsushi Kittaka, Nozomi Saito, Toshie Fujishima
  • 2-substituted vitamin d derivatives
    Publication number: 20050131242
    Abstract: According to the present invention, there are provided vitamin D derivatives represented by the following general formula (1): wherein R1 and R2 may be the same or different, and each represents a straight chain or branched chain alkyl group optionally substituted by a hydroxyl group, and R3 represents a straight chain or branched chain alkyl group optionally substituted by a hydroxyl group.
    Type: Application
    Filed: December 25, 2002
    Publication date: June 16, 2005
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroaki Takayama, Toshie Fujishima, Atsushi Kittaka
  • Vitamin d derivatives having substituents at the 2 alpha-position
    Publication number: 20030022872
    Abstract: An object of the present invention is to synthesize a novel vitamin D derivative having a substituent at the 2&agr;-position.
    Type: Application
    Filed: August 27, 2002
    Publication date: January 30, 2003
    Inventors: Hiroaki Takayama, Atsushi Kittaka, Yoshitomo Suhara, Toshie Fujishima