Patents by Inventor Atsushi Muro
Atsushi Muro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230381268Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: August 4, 2023Publication date: November 30, 2023Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Publication number: 20230113303Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: December 8, 2022Publication date: April 13, 2023Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Publication number: 20220257696Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: May 4, 2022Publication date: August 18, 2022Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Publication number: 20220008501Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: September 23, 2021Publication date: January 13, 2022Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Publication number: 20210161996Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: October 26, 2020Publication date: June 3, 2021Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Publication number: 20200206305Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: March 12, 2020Publication date: July 2, 2020Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Publication number: 20190060395Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: October 26, 2018Publication date: February 28, 2019Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Publication number: 20180185437Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: February 27, 2018Publication date: July 5, 2018Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Publication number: 20170087206Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: December 13, 2016Publication date: March 30, 2017Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Patent number: 9408835Abstract: A pharmaceutical composition containing, as the active ingredient, 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, of which the solubility in an acidic pH region is different from that in a neutral pH region, with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance, is provided. The pharmaceutical composition for oral administration of the present invention contains 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide or a pharmaceutically acceptable salt thereof, and a hydrophilic lubricant, and is useful as a pharmaceutical composition for oral administration with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance.Type: GrantFiled: March 28, 2014Date of Patent: August 9, 2016Assignee: ASTELLAS PHARMA INC.Inventors: Seiji Takae, Hiroyuki Kojima, Atsushi Sakurai, Tetsuya Tamura, Hiroaki Tasaki, Atsushi Muro
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Publication number: 20160045479Abstract: A pharmaceutical composition containing, as the active ingredient, 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, of which the solubility in an acidic pH region is different from that in a neutral pH region, with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance, is provided. The pharmaceutical composition for oral administration of the present invention contains 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide or a pharmaceutically acceptable salt thereof, and a hydrophilic lubricant, and is useful as a pharmaceutical composition for oral administration with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance.Type: ApplicationFiled: March 28, 2014Publication date: February 18, 2016Applicant: ASTELLAS PHARMA INC.Inventors: SEIJI TAKAE, HIROYUKI KOJIMA, ATSUSHI SAKURAI, TETSUYA TAMURA, HIROAKI TASAKI, ATSUSHI MURO
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Publication number: 20140242158Abstract: The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.Type: ApplicationFiled: September 28, 2012Publication date: August 28, 2014Applicant: Astellas Pharma, Inc.Inventors: Mare Nishiura, Kenichi Ashihara, Kanehira Imai, Atsushi Muro, Tsukasa Nishikawahara
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Patent number: 5013711Abstract: The image-receiving sheet of the present invention is used in combination with a heat transfer sheet having a colorant layer containing a sublimable dye on one surface of a substrate sheet. The image-receiving sheet includes a receiving layer containing a synthetic resin and an antioxidant including a specific structure as described above for receiving the sublimable dye migrated from the colorant layer of the heat transfer sheet formed on one surface of a substrate sheet, and therefore it can give a hard copy having extremely high light resistance of the recorded image of which color will be faded only with difficulty even when stored for a long term.Type: GrantFiled: March 8, 1990Date of Patent: May 7, 1991Assignee: Dai Nippon Insatsu Kabushiki KaishaInventors: Noritaka Egashira, Kenichiro Suto, Atsushi Muro
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Patent number: 4929591Abstract: The image-receiving sheet of the present invention is used in combination with a heat transfer sheet having a colorant layer containing a sublimable dye on one surface of a substrate sheet. The image-receiving sheet includes a receiving layer containing a synthetic resin and an antioxidant including a specific structure as described above for receiving the sublimable dye migrated from the colorant layer of the heat transfer sheet formed on one surface of a substrate sheet, and therefore it can give a hard copy having extremely high light resistance of the recorded image of which color will be faded only with difficulty even when stored for a long term.Type: GrantFiled: November 9, 1988Date of Patent: May 29, 1990Assignee: Dai Nippon Insatsu Kabushiki KaishaInventors: Noritaka Egashira, Kenichiro Suto, Atsushi Muro