Patents by Inventor Atsushi Okuma

Atsushi Okuma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240139242
    Abstract: The technology described herein is directed to compositions comprising components of multi-component CALs or CARs, e.g., a TCR recognition domain; and one or both of: (a) an intracellular signaling domain; and (b) a first-type protein interaction domain. Further provided herein are methods for treating or preventing an autoimmune disease, a transplant rejection, or graft versus host disease.
    Type: Application
    Filed: October 16, 2020
    Publication date: May 2, 2024
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Mohammadreza PAKYARI, Wilson WONG, Atsushi OKUMA, Curtis CETRULO
  • Publication number: 20240116028
    Abstract: A method of regenerating an acid gas adsorption device includes the steps of: causing an acid gas to be adsorbed to an acid gas adsorption material by supplying a gas including the acid gas to an acid gas adsorption device so that the gas is brought into contact with an acid gas adsorption layer; causing the acid gas to be desorbed from the acid gas adsorption material; removing the acid gas adsorption layer of the acid gas adsorption device, which has been subjected to the step of causing the acid gas to be adsorbed and the step of causing the acid gas to be desorbed, from a surface of a base material; and forming an acid gas adsorption layer including a porous carrier and an acid gas adsorption material on the surface of the base material from which the acid gas adsorption layer has been removed.
    Type: Application
    Filed: December 20, 2023
    Publication date: April 11, 2024
    Applicant: NGK INSULATORS, LTD.
    Inventors: Yusuke OKUMA, Yukinari SHIBAGAKI, Hirofumi KAN, Kazuki IIDA, Atsushi TORII, Kosuke NAKAGAWA
  • Publication number: 20230321183
    Abstract: The technology described herein is directed to compositions comprising components of multi-component CALs or CARs, e.g., a TCR recognition domain; and one or both of: (a) an intracellular signaling domain; and (b) a first-type protein interaction domain. Further provided herein are methods for treating or preventing an autoimmune disease, a transplant rejection, or graft versus host disease.
    Type: Application
    Filed: June 16, 2023
    Publication date: October 12, 2023
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Mohammadreza PAKYARI, Wilson WONG, Atsushi OKUMA, Curtis CETRULO
  • Patent number: 11723950
    Abstract: The technology described herein is directed to compositions comprising components of multi-component CALs or CARs, e.g., a TCR recognition domain; and one or both of: (a) an intracellular signaling domain; and (b) a first-type protein interaction domain. Further provided herein are methods for treating or preventing an autoimmune disease, a transplant rejection, or graft versus host disease.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: August 15, 2023
    Assignees: TRUSTEES OF BOSTON UNIVERSITY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Mohammadreza Pakyari, Wilson Wong, Atsushi Okuma, Curtis Cetrulo
  • Publication number: 20220226505
    Abstract: An object of the invention is to provide a novel pharmaceutical composition. The pharmaceutical composition of the disclosure contains a DNA encoding a suicide gene having at least one intron sequence. The intron sequence has a donor sequence or an acceptor sequence to be used in a tumor cell with abnormal splicing not in a normal cell. In a transcript of the DNA, the suicide gene is expressed when the intron is abnormally spliced and the suicide gene is not expressed when the intron is not abnormally spliced.
    Type: Application
    Filed: January 14, 2022
    Publication date: July 21, 2022
    Inventor: Atsushi OKUMA
  • Publication number: 20210113653
    Abstract: The technology described herein is directed to compositions comprising components of multi-component CALs or CARs, e.g., a TCR recognition domain; and one or both of: (a) an intracellular signaling domain; and (b) a first-type protein interaction domain. Further provided herein are methods for treating or preventing an autoimmune disease, a transplant rejection, or graft versus host disease.
    Type: Application
    Filed: October 16, 2020
    Publication date: April 22, 2021
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, THE GENERAL HOSPITAL CORPORATION
    Inventors: Mohammadreza PAKYARI, Wilson WONG, Atsushi OKUMA, Curtis CETRULO
  • Patent number: 5041508
    Abstract: An anaerobic composition comprising a polymerizable monomer having at least one ethylenic double bond, a free radical initiator and at least one azole compound.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: August 20, 1991
    Assignee: Three Bond Co., Ltd.
    Inventors: Katsunori Haruna, Shuji Mochizuki, Atsushi Okuma
  • Patent number: 4985523
    Abstract: An anaerobically curing adhesive sealing composition comprising (A) a mono(meth)acrylate monomer represented by formula (I) ##STR1## wherein R.sub.1 represents a hydrogen atom or a methyl group; and R.sub.2 represents ##STR2## and (B) a (meth)acrylate prepolymer having a urethane structure in the main chain thereof and having an average molecular weight of 10,000 or more and further containing (C) a (meth)acrylate prepolymer having a urethane structure in the main chain thereof and an average molecular weight of at most 5,000. The sealing composition exhibits, upon curing, excellent elasticity and properties to follow an adherend while retaining excellent resistance to oil and heat as possessed by acrylate type reactive sealing compositions.
    Type: Grant
    Filed: August 28, 1989
    Date of Patent: January 15, 1991
    Assignee: Three Bond Co., Ltd.
    Inventors: Shuji Mochizuki, Atsushi Okuma, Katsunori Haruna
  • Patent number: 4814427
    Abstract: A primer for .alpha.-cyanoacrylate-based resin compositions, which is disclosed herein, comprises (A) a compound selected from the group consisting of benzene ring compounds having aldehyde group and nitrogen or oxygen atom-containing heterocyclic compounds having aldehyde group, and (B) an organic amine compound. In bonding, coating or printing various non-polar or highly crystallized resins, the primer exhibits a high bonding strength by a simple procedure.
    Type: Grant
    Filed: November 6, 1987
    Date of Patent: March 21, 1989
    Assignee: Three Bond Company, Ltd.
    Inventors: Kazuhide Fukuda, Atsushi Okuma, Miwako Ota