Abstract: A blood vessel detection device comprises: a first irradiation unit for irradiating a predetermined site of a subject with light of a first wavelength that is absorbed less by hemoglobin or water and light of a second wavelength that is absorbed more by hemoglobin or water than the first wavelength; a second irradiation unit for irradiating the predetermined site with light of a third wavelength that is absorbed less by hemoglobin; a light intensity detection unit for detecting the intensity of light emitted from the subject at one or more positions spaced apart by a predetermined distance from the light irradiation positions of the first and second irradiation units or one or more contiguous positions; and a control unit that calculates blood vessel depth information, calculates blood vessel angle information, and determines an optimal position for measurement based on the blood vessel depth information and the blood vessel angle information.

Abstract: The present invention is directed to an apparatus and a method that make it possible to identify a blood vessel location. The apparatus includes a radiation unit, an optical intensity detection unit, and a control unit.

Abstract: A biological sample solution is ionized by electrospray and the sample solution is irradiated with an infrared laser beam to dissociate biological macromolecules into the constituents thereof. As a result, only non-covalent bonds of the biological macromolecules can be selectively severed and analyzed.

Abstract: A biological sample can be subjected to measurement, description and ionization of ions is possible under atmospheric pressure without undergoing pretreatment. Imaging having a resolution on the nanometer order can be performed. An STM needle (probe) of an XYZ-axis-drive piezoelectric element is oscillated along the Z axis to contact the sample to a depth on the nanometer order and capture molecules at the needle tip. A pulsed high voltage is applied to the needle, achieving needle electrospray. The sample molecules are then desorbed and ionized, and mass spectrometry is carried out. The needle is swept in the XY directions, oscillation is repeated and an image obtained by molecular imaging of a nanometer area of the biological sample is measured. The probe may be brought into contact with a droplet produced at the tip of a capillary connected to the outlet port of a liquid chromatograph to capture a sample.

Abstract: A biological sample can be subjected to measurement, description and ionization of ions is possible under atmospheric pressure without undergoing pretreatment. Imaging having a resolution on the nanometer order can be performed. An STM needle (probe) of an XYZ-axis-drive piezoelectric element is oscillated along the Z axis to contact the sample to a depth on the nanometer order and capture molecules at the needle tip. A pulsed high voltage is applied to the needle, achieving needle electrospray. The sample molecules are then desorbed and ionized, and mass spectrometry is carried out. The needle is swept in the XY directions, oscillation is repeated and an image obtained by molecular imaging of a nanometer area of the biological sample is measured. The probe may be brought into contact with a droplet produced at the tip of a capillary connected to the outlet port of a liquid chromatograph to capture a sample.

Abstract: A biological sample solution is ionized by electrospray and the sample solution is irradiated with an infrared laser beam to dissociate biological macromolecules into the constituents thereof. As a result, only non-covalent bonds of the biological macromolecules can be selectively severed and analyzed.