Patents by Inventor Atsutaka Minagawa

Atsutaka Minagawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL T-CELL RECEPTOR
    Publication number: 20230257708
    Abstract: Provided is a T cell receptor containing, as ? chain complementarity determining regions, respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 1 to 3, or respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 4 to 6, as ? chain complementarity determining regions, respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 7 to 9, or respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 10 to 12, and capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 27 or a complex of the peptide and HLA-A24.
    Type: Application
    Filed: February 6, 2023
    Publication date: August 17, 2023
    Inventors: Tetsuya Nakatsura, Toshiaki Yoshikawa, Yasushi Uemura, Kyoko Fukuda, Shin Kaneko, Atsutaka Minagawa, Yoshiaki Kassai, Atsushi Matsuda
  • T-cell receptor
    Patent number: 11603519
    Abstract: Provided is a T cell receptor capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 27 or a complex of the peptide and HLA-A24. A T cell receptor capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 28 or a complex of the peptide and HLA-A02. Disclosed T cell receptors are useful in treating or avoiding cancers which are associated with expression of glypican-3.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: March 14, 2023
    Assignees: National Cancer Center Japan, Kyoto University, Takeda Pharmaceutical Company Limited
    Inventors: Tetsuya Nakatsura, Toshiaki Yoshikawa, Yasushi Uemura, Kyoko Fukuda, Shin Kaneko, Atsutaka Minagawa, Yoshiaki Kassai, Atsushi Matsuda
  • Method for induction of T cells from pluripotent stem cells
    Patent number: 10660915
    Abstract: The present invention provides a method for efficiently inducing CD8-positive T cells by adding vitamin C to the medium in the steps of induction of the CD8-positive T cells from pluripotent stem cells. The present invention also provides a method for efficiently inducing CD8-positive T cells by performing culture in a medium supplemented with an adrenocortical hormone agent in the step of induction of the CD8-positive T cells from CD4/CD8 double-positive T cells.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: May 26, 2020
    Assignee: Kyoto University
    Inventors: Shin Kaneko, Atsutaka Minagawa, Yutaka Yasui
  • NOVEL T-CELL RECEPTOR
    Publication number: 20200010804
    Abstract: Provided is a T cell receptor containing, as ? chain complementarity determining regions, respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 1 to 3, or respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 4 to 6, as ? chain complementarity determining regions, respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 7 to 9, or respective amino acid sequences of CDR1 to CDR3 respectively shown in SEQ ID NOs: 10 to 12, and capable of binding to a peptide having the amino acid sequence shown in SEQ ID NO: 27 or a complex of the peptide and HLA-A24.
    Type: Application
    Filed: February 5, 2018
    Publication date: January 9, 2020
    Inventors: Tetsuya Nakatsura, Toshiaki Yoshikawa, Yasushi Uemura, Kyoko Fukuda, Shin Kaneko, Atsutaka Minagawa, Yoshiaki Kassai, Atsushi Matsuda
  • METHOD FOR INDUCING T CELLS FOR IMMUNOCYTOTHERAPY FROM PLURIPOTENT STEM CELLS
    Publication number: 20170369850
    Abstract: Provided is a method for inducing T cells for a cell-based immunotherapy, comprising the steps of: (1) providing Rag 1 and/or Rag 2 gene knockout human pluripotent stem cells bearing genes encoding a T cell receptor specific for a desired antigen, and (2) inducing T cells from the pluripotent stem cells of step (1). Further provided are a cell-based immunotherapy method that uses the T cells for the cell-based immunotherapy and an iPS cell bank for the cell-based immunotherapy.
    Type: Application
    Filed: July 17, 2015
    Publication date: December 28, 2017
    Inventors: Shin Kaneko, Hiroshi Kawamoto, Kyoko Masuda, Atsutaka Minagawa, Akitsu Hotta, Yutaka Shimazu, Hiroshi Ichise
  • METHOD FOR INDUCTION OF T CELLS FROM PLURIPOTENT STEM CELLS
    Publication number: 20170326175
    Abstract: The present invention provides a method for efficiently inducing CD8-positive T cells by adding vitamin C to the medium in the steps of induction of the CD8-positive T cells from pluripotent stem cells. The present invention also provides a method for efficiently inducing CD8-positive T cells by performing culture in a medium supplemented with an adrenocortical hormone agent in the step of induction of the CD8-positive T cells from CD4/CD8 double-positive T cells.
    Type: Application
    Filed: November 13, 2015
    Publication date: November 16, 2017
    Inventors: Shin Kaneko, Atsutaka Minagawa, Yutaka Yasui