Patents by Inventor Atsuya Takami

Atsuya Takami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calcium receptor active compounds
    Patent number: 7816408
    Abstract: A novel calcium receptor active compound having the formula is provided: Ar1—[CR1R2]p—X—[CR3R4]q—[CR5R6]—NR7—[CR8R9]—Ar2 wherein: Ar1 is selected from the group consisting of aryl, heteroaryl, bis(arylmethyl)amino, bis(heteroarylmethyl)amino and arylmethyl(heteroarylmethyl)amino; X is selected from the group consisting of oxygen, sulfur, sulfinyl, sulfonyl, carbonyl and amino; R1, R2, R3, R4, R5, R6, R7, R8 and R9 are, for example, hydrogen or alkyl; Ar2 is selected from the group consisting of aryl and heteroaryl; p is an integer of from 0 to 6, inclusive; and, q is an integer of from 0 to 14, inclusive.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: October 19, 2010
    Assignee: NPS Pharmaceuticals, Inc.
    Inventors: Teruyuki Saki, Atsuya Takami, Rika Nagao
  • Calcium receptor active compounds
    Publication number: 20090176993
    Abstract: A novel calcium receptor active compound having the formula is provided: Ar1—[CR1R2]p—X—[CR3R4]q—[CR5R6]—NR7—[CR8R9]—Ar2 wherein: Ar1 is selected from the group consisting of aryl, heteroaryl, bis(arylmethyl)amino, bis(heteroarylmethyl)amino and arylmethyl(heteroarylmethyl)amino; X is selected from the group consisting of oxygen, sulfur, sulfinyl, sulfonyl, carbonyl and amino; R1, R2, R3, R4, R5, R6, R7, R8 and R9 are, for example, hydrogen or alkyl; Ar2 is selected from the group consisting of aryl and heteroaryl; p is an integer of from 0 to 6, inclusive; and, q is an integer of from 0 to 14, inclusive.
    Type: Application
    Filed: March 13, 2003
    Publication date: July 9, 2009
    Inventors: Teruyuki Sakai, Atsuya Takami, Rika Nagao
  • Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
    Patent number: 7217722
    Abstract: An objective of the present invention is to provide compounds having Rho kinase inhibitory activity. The compounds according to the present invention are those represented by formula (I) or pharmaceutically acceptable salts or solvates thereof: Het—X—Z??(I) wherein Het represents a monocyclic or bicyclic heterocyclic group containing at least one nitrogen atom, for example, pyridyl or phthalimide; X represents group (i) —NH—C(?O)—NH—Q1-, group (ii) —NH—C(?O)—Q2-, wherein Q1 and Q2 represent a bond, alkylene, or alkenylene, or the like; and Z represents hydrogen, halogen, a monocyclic, bicyclic, or tricyclic carbocyclic group, a heterocyclic group or the like, for example, optionally substituted phenyl.
    Type: Grant
    Filed: January 2, 2001
    Date of Patent: May 15, 2007
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Atsuya Takami, Hiroshi Iijima, Masayuki Iwakubo, Yuji Okada
  • Calcium receptor-active compounds
    Patent number: 6939895
    Abstract: A novel calcium receptor active compound having the formula is provided: Ar1—[CR1R2]p—X—[CR3R4]q—[CR5R6]—NR7—[CR8R9]—Ar2 wherein: Ar1 is selected from the group consisting of aryl, heteroaryl, bis(arylmethyl)amino, bis(heteroarylmethyl)amino and arylmethyl(heteroarylmethyl)amino; X is selected from the group consisting of oxygen, sulfur, sulfinyl, sulfonyl, carbonyl and amino; R1, R2, R3, R4, R5, R6, R7, R8 and R9 are, for example, hydrogen or alkyl; Ar2 is selected from the group consisting of aryl and heteroaryl; p is an integer of from 0 to 6, inclusive; and, q is an integer of from 0 to 14, inclusive.
    Type: Grant
    Filed: December 19, 2002
    Date of Patent: September 6, 2005
    Assignee: NPS Pharmaceuticals, Inc.
    Inventors: Teruyuki Sakai, Atsuya Takami, Rika Nagao
  • Calcium receptor-active compounds
    Patent number: 6750255
    Abstract: A novel calcium receptor active compound having the formula is provided: Ar1—[CR1R2]p—X—[CR3R4]q—[CR5R6]—NR7—[CR8R9]—Ar2 wherein: Ar1 is selected from the group consisting of aryl, heteroaryl, bis(arylmethyl)amino, bis(heteroarylmethyl)amino and arylmethyl(heteroarylmethyl)amino; X is selected from the group consisting of oxygen, sulfur, sulfinyl, sulfonyl, carbonyl and amino; R1, R2, R3, R4, R5, R6, R7, R8 and R9 are, for example, hydrogen or alkyl; Ar2 is selected from the group consisting of aryl and heteroaryl; p is an integer of from 0 to 6, inclusive; and, q is an integer of from 0 to 14, inclusive.
    Type: Grant
    Filed: January 17, 2002
    Date of Patent: June 15, 2004
    Assignees: NPS Pharmaceuticals, Inc., Kirin Beer Kabushiki
    Inventors: Teruyuki Sakai, Atsuya Takami, Rika Nagao
  • Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
    Publication number: 20040102437
    Abstract: Compounds having an Rho kinase inhibitory activity. These compounds include the compound of general formula (I): Het-X-Z, pharmaceutically acceptable salts thereof and solvates of the same, wherein Het represents a monocyclic or dicyclic heterocycle group containing at least one nitrogen atom (for example, pyridyl, phthalimido); X represents (i) an —NH—C(═O)—NH-Q1- group, (ii) an —NH—C(═O)-Q2- group, etc. (wherein Q1 and Q2 represent each a bond, alkylene or alkenylene); and Z represents hydrogen, halogeno, a monocyclic, dicyclic ortricyclic carbon cycle or heterocycle, etc. (for example, optionally substituted phenyl).
    Type: Application
    Filed: May 19, 2003
    Publication date: May 27, 2004
    Inventors: Atsuya Takami, Hiroshi Iijima, Masayuki Iwakubo, Yuji Okada
  • Calcium receptor active compounds
    Publication number: 20030176485
    Abstract: A novel calcium receptor active compound having the formula is provided:
    Type: Application
    Filed: November 21, 2002
    Publication date: September 18, 2003
    Applicant: NPS Pharmaceuticals, Inc.
    Inventors: Teruyuki Sakai, Atsuya Takami, Rika Nagao
  • Calcium receptor-active compounds
    Publication number: 20030144526
    Abstract: A novel calcium receptor active compound having the formula is provided:
    Type: Application
    Filed: December 19, 2002
    Publication date: July 31, 2003
    Applicant: NPS Pharmaceuticals, Inc.
    Inventors: Teruyuki Sakai, Atsuya Takami, Rika Nagao
  • Calcium receptor-active compounds
    Publication number: 20020107406
    Abstract: A novel calcium receptor active compound having the formula is provided:
    Type: Application
    Filed: January 17, 2002
    Publication date: August 8, 2002
    Applicant: NPS Pharmaceuticals, Inc.
    Inventors: Teruyuki Sakai, Atsuya Takami, Rika Nagao
  • Calcium receptor active compounds
    Patent number: 6362231
    Abstract: A novel calcium receptor active compound having the formula is provided: Ar1—[CR1R2]P—X—[CR3R4]q—[CR5R6]—NR7—[CR8R9]—Ar2 wherein: Ar1 is selected from the group consisting of aryl, heteroaryl, bis(arylmethyl)amino, bis(heteroarylmethyl)amino and arylmethyl(heteroarylmethyl)amino; X is selected from the group consisting of oxygen, sulfur, sulfinyl, sulfonyl, carbonyl and amino; R1, R2, R3, R4, R5, R6, R7, R8 and R9 are, for example, hydrogen or alkyl; Ar2 is selected from the group consisting of aryl and heteroaryl; p is an integer of from 0 to 6, inclusive; and, q is an integer of from 0 to 14, inclusive.
    Type: Grant
    Filed: June 6, 1999
    Date of Patent: March 26, 2002
    Assignee: NPS Pharmaceuticals, Inc.
    Inventors: Teruyuki Sakai, Atsuya Takami, Rika Nagao