Abstract: The invention relates to promoting autophagy in the treatment or prevention of autophagy related disorders, such as various forms of cancer; liver disease, myopathies of various origin; cardiovascular disorders, neurodegenerative disorders by using the compounds of the invention or their pharmaceutically acceptable salts.

Abstract: The invention relates to blocking autophagy in the treatment or prevention of various forms of cancer by using the compounds of the invention or their pharmaceutically acceptable salts. Also described are pharmaceutical compositions comprising the compounds of the invention or pharmaceutically acceptable salts thereof. Pharmaceutical compositions may be formulated as, but not limited to, tablets, capsules, solutions and ointments. The invention further relates to suitable pharmaceutical compositions, which contain the compounds of the invention as a combined preparation for simultaneous, separate or sequential use for the treatment and prevention of cancer.