Patents by Inventor Attila Mezo

Attila Mezo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multistage process for the preparation of highly pure deferoxamine mesylate salt
    Patent number: 6858414
    Abstract: The present invention provides a purification process whereby deferoxamine B produced by a microorganism and in mixture with other polyhydroxamates produced by the microorganism may be converted into its mesylate salt substantially free of the other polyhydroxamates and substantially free of chloride ion. The process includes adsorption and desorption of the deferoxamine B on an adsorption resin, direct precipitation of the deferoxamine free base out of the eluent from the adsorption resin, contacting of the deferoxamine B free base with methanesulfonic acid and isolation of the deferoxamine B mesylate salt by precipitation. This process minimizes decomposition of deferoxamine B.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: February 22, 2005
    Assignee: Biogal Gyógyszergyár Rt.
    Inventors: Vilmos Keri, Zoltan Czovek, Attila Mezo
  • Multistage process for the preparation of highly pure deferoxamine mesylate salt
    Publication number: 20030059905
    Abstract: The present invention provides a purification process whereby deferoxamine B produced by a microorganism and in mixture with other polyhydroxamates produced by the microorganism may be converted into its mesylate salt substantially free of the other polyhydroxamates and substantially free of chloride ion. The process includes adsorption and desorption of the deferoxamine B on an adsorption resin, direct precipitation of the deferoxamine free base out of the eluent from the adsorption resin, contacting of the deferoxamine B free base with methanesulfonic acid and isolation of the deferoxamine B mesylate salt by precipitation. This process minimizes decomposition of deferoxamine B.
    Type: Application
    Filed: June 18, 2002
    Publication date: March 27, 2003
    Inventors: Vilmos Keri, Zoltan Czovek, Attila Mezo