Patents by Inventor Attila T. Lorincz

Attila T. Lorincz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8227190
    Abstract: The present invention relates to an accurate, sensitive, and efficient sequential or concurrently sequential method for molecular diagnosis of human papillomavirus (HPV)-based disease, where the method improves the accuracy and reliability of diagnostic and prognostic assessments of HPV-based disease. The method of the invention comprises a primary screen of a sample for HPV nucleic acids, followed by a secondary screen for molecular markers, such as proliferation and cell cycle control group protein markers. The sequential or concurrently sequential method significantly reduces the number of false positive results.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: July 24, 2012
    Assignee: Qiagen Gaithersburg, Inc.
    Inventors: Inna R. Williams, Attila T. Lorincz, Aisling O'Hara
  • Publication number: 20110097708
    Abstract: This invention provides novel methods for assessing HPV infection. Gene expression levels are used to assess the progression of HPV infection from benign to malignant growth. Also provided are kits for carrying out the methods of this invention.
    Type: Application
    Filed: December 22, 2010
    Publication date: April 28, 2011
    Applicant: QIAGEN GAITHERSBURG INC.
    Inventors: Attila T. LORINCZ, James G. Lazar
  • Patent number: 7879546
    Abstract: This invention provides methods for assessing HPV infection. Gene expression levels are used to assess the progression of HPV infection from benign to malignant growth. Also provided are kits for carrying out the methods of this invention.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: February 1, 2011
    Assignee: Qiagen Gaithersburg Inc.
    Inventors: Attila T. Lorincz, James G. Lazar
  • Patent number: 7399589
    Abstract: The present invention provides a hybridization method and kit for the detection and measurement of biological molecules. A test sample containing the biological molecules of interest is hybridized with an unlabeled or optionally a detectably-labeled complementary biomolecule to form a double-stranded hybrid immobilized to a solid phase. The immobilized hybrid may be detected with an entity which specifically recognizes an RNA:DNA hybrid, followed by analyses and quantification. Therefore, the present invention provides a method and kit to detect and measure biological molecules that is simple to use, highly specific, sensitive, and accurate for screening a plurality of biological molecules.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: July 15, 2008
    Assignee: Digene Corporation
    Inventors: James G. Lazar, Joan M. Zakel, Christina M. Strange, Inna R. Williams, Attila T. Lorincz, Abel De La Rosa
  • Patent number: 7371518
    Abstract: This invention provides a novel universal collection medium for cell collection. The medium allows for the first time the ability to perform cytology and direct molecular analysis on cells preserved in a single sample. This invention also provides novel methods for analyzing cells to assess human conditions.
    Type: Grant
    Filed: January 24, 2003
    Date of Patent: May 13, 2008
    Assignee: Digene Corporation
    Inventors: Attila T. Lorincz, Yanlin Tang
  • Patent number: 7361460
    Abstract: The present invention relates to an accurate, sensitive, and efficient sequential or concurrently sequential method for molecular diagnosis of human papillomavirus (HPV)-based disease, where the method improves the accuracy and reliability of diagnostic and prognostic assessments of HPV-based disease. The method of the invention comprises a primary screen of a sample for HPV nucleic acids, followed by a secondary screen for molecular markers, such as proliferation and cell cycle control group protein markers. The sequential or concurrently sequential method significantly reduces the number of false positive results.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: April 22, 2008
    Assignee: Digene Corporation
    Inventors: Inna R. Williams, Attila T. Lorincz, Aisling O'Hara
  • Patent number: 7291455
    Abstract: This invention provides novel methods for assessing HPV infection. Gene expression levels are used to assess the progression of HPV infection from benign to malignant growth. Also provided are kits for carrying out the methods of this invention.
    Type: Grant
    Filed: October 4, 2001
    Date of Patent: November 6, 2007
    Assignee: Digene Corporation
    Inventors: Attila T. Lorincz, James G. Lazar
  • Patent number: 6969585
    Abstract: This invention provides a novel universal collection medium for cell collection. The medium allows for the first time the ability to perform cytology and direct molecular analysis on cells preserved in a single sample. This invention also provides novel methods for analyzing cells to assess human conditions.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: November 29, 2005
    Assignee: Digene Corporation
    Inventors: Attila T. Lorincz, Yanlin Tang
  • Publication number: 20040202996
    Abstract: The present invention relates to an accurate, sensitive, and efficient sequential or concurrently sequential method for molecular diagnosis of human papillomavirus (HPV)-based disease, where the method improves the accuracy and reliability of diagnostic and prognostic assessments of HPV-based disease. The method of the invention comprises a primary screen of a sample for HPV nucleic acids, followed by a secondary screen for molecular markers, such as proliferation and cell cycle control group protein markers. The sequential or concurrently sequential method significantly reduces the number of false positive results.
    Type: Application
    Filed: April 11, 2003
    Publication date: October 14, 2004
    Inventors: Inna R. Williams, Attila T. Lorincz, Aisling O'Hara
  • Publication number: 20040180362
    Abstract: The present invention provides a hybridization method and kit for the detection and measurement of biological molecules. A test sample containing the biological molecules of interest is hybridized with an unlabeled or optionally a detectably-labeled complementary biomolecule to form a double-stranded hybrid immobilized to a solid phase. The immobilized hybrid may be detected with an entity which specifically recognizes an RNA:DNA hybrid, followed by analyses and quantification. Therefore, the present invention provides a method and kit to detect and measure biological molecules that is simple to use, highly specific, sensitive, and accurate for screening a plurality of biological molecules.
    Type: Application
    Filed: December 11, 2003
    Publication date: September 16, 2004
    Inventors: James G. Lazar, Joan M. Zakel, Christina M. Strange, Inna R. Williams, Attila T. Lorincz, Abel De La Rosa
  • Patent number: 6686151
    Abstract: The present invention provides a hybridization method and kit for the detection and measurement of biological molecules. A test sample containing the biological molecules of interest is hybridized with an unlabeled or optionally a detectably labeled complementary biomolecule to form a double-stranded hybrid immobilized to a solid phase. The immobilized hybrid may be detected with an entity which specifically recognizes an RNA:DNA hybrid, followed by analyses and quantification. Therefore, the present invention provides a method and kit to detect and measure biological molecules that is simple to use, highly specific, sensitive, and accurate for screening a plurality of biological molecules.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: February 3, 2004
    Assignee: Digene Corporation
    Inventors: James G. Lazar, Joan M. Zakel, Christina M. Strange, Inna R. Williams, Attila T. Lorincz, Abel De La Rosa
  • Publication number: 20030119049
    Abstract: This invention provides a novel universal collection medium for cell collection. The medium allows for the first time.the ability to perform cytology and direct molecular analysis on cells preserved in a single sample. This invention also provides novel methods for analyzing cells to assess human conditions.
    Type: Application
    Filed: January 24, 2003
    Publication date: June 26, 2003
    Inventors: Attila T. Lorincz, Yanlin Tang
  • Publication number: 20030091992
    Abstract: This invention provides a novel universal collection medium for cell collection. The medium allows for the first time the ability to perform cytology and direct molecular analysis on cells preserved in a single sample. This invention also provides novel methods for analyzing cells to assess human conditions.
    Type: Application
    Filed: December 11, 1998
    Publication date: May 15, 2003
    Inventors: ATTILA T. LORINCZ, YANLIN TANG
  • Publication number: 20020127545
    Abstract: This invention provides novel methods for assessing HPV infection. Gene expression levels are used to assess the progression of HPV infection from benign to malignant growth. Also provided are kits for carrying out the methods of this invention.
    Type: Application
    Filed: October 4, 2001
    Publication date: September 12, 2002
    Inventors: Attila T. Lorincz, James G. Lazar
  • Patent number: 6355424
    Abstract: This invention provides novel methods for assessing HPV infection. Gene expression levels are used to assess the progression of HPV infection from benign to malignant growth. Also provided are kits for carrying out the methods of this invention.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: March 12, 2002
    Assignee: Digene Corporation
    Inventors: Attila T. Lorincz, James G. Lazar
  • Patent number: 6136535
    Abstract: Continuous amplification reaction provide a method of amplifying a specific nucleic acid without the need to cycle a reaction. The method produces RNA transcripts which can be detected by a variety of methods. Amplification and detection kits are also provided.
    Type: Grant
    Filed: August 10, 1998
    Date of Patent: October 24, 2000
    Assignee: Digene Corporation
    Inventors: Attila T. Lorincz, Abel DeLaRosa
  • Patent number: 6027897
    Abstract: Continuous amplification reaction provide a method of amplifying a specific nucleic acid without the need to cycle a reaction. The method produces RNA transcripts which can be detected by a variety of methods. Amplification and detection kits are also provided.
    Type: Grant
    Filed: June 8, 1998
    Date of Patent: February 22, 2000
    Assignee: Digene Corporation
    Inventors: Attila T. Lorincz, Abel De La Rosa
  • Patent number: 4908306
    Abstract: Nucleic acid hybridization probes for human papillomavirus types and particularly human papillomavirus type 56; and methods for employing the same.
    Type: Grant
    Filed: April 27, 1989
    Date of Patent: March 13, 1990
    Assignee: Life Technologies, Inc.
    Inventor: Attila T. Lorincz
  • Patent number: 4849332
    Abstract: Nucleic acid hybridization probes for human papillomavirus types and particularly human papillomavirus type 35; and methods for employing the same.
    Type: Grant
    Filed: May 26, 1987
    Date of Patent: July 18, 1989
    Assignee: Life Technologies, Inc.
    Inventor: Attila T. Lorincz
  • Patent number: 4849331
    Abstract: Nucleic acid hybridization probes for human papillomavirus types and particularly human papillomavirus type 44; and methods for employing the same.
    Type: Grant
    Filed: June 9, 1987
    Date of Patent: July 18, 1989
    Assignee: Life Technologies, Inc.
    Inventor: Attila T. Lorincz