Patents by Inventor Aude THIRIOT

Aude THIRIOT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATING VENULENESS OF ENDOTHELIAL CELLS
    Publication number: 20240417694
    Abstract: Disclosed herein are genes which are differentially expressed in venule endothelial cells (V-ECs) compared to non-venule endothelial cells (NV-ECs), and methods and compositions relating to those genes. In particular, described herein are methods of reducing the venuleness of endothelial cells (ECs) for treating inflammatory diseases, and methods of increasing the venuleness of ECs for treating cancers.
    Type: Application
    Filed: May 16, 2024
    Publication date: December 19, 2024
    Inventors: UIrich H. VON ANDRIAN, Aude THIRIOT, Kristin RATTAY, Munir M. MOSAHEB, Rohit GARG
  • Amphiphile-Polymer Particles
    Publication number: 20200206145
    Abstract: This invention relates to amphiphile-polymer particles, compositions, methods of making, and methods of use thereof.
    Type: Application
    Filed: March 9, 2020
    Publication date: July 2, 2020
    Inventors: Jinjun Shi, Xi Zhu, Omid C. Farokhzad, Xiaoding Xu, Yanlan Liu, Aude Thiriot, Ulrich Von Andrian
  • Amphiphile-polymer particles
    Patent number: 10583091
    Abstract: This invention relates to amphiphile-polymer particles comprising obtaining a first solution comprising a water-insoluble polymer, a payload and a first amphiphile in a water-miscible solvent; mixing the first solution with an aqueous second solution to form an aqueous composition comprising a particle comprising a water-insoluble polymeric core comprising the water-insoluble polymer; the payload; and the first amphiphile.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: March 10, 2020
    Assignees: The Brigham and Women's Hospital, Inc., President and Fellows of Harvard College
    Inventors: Jinjun Shi, Xi Zhu, Omid C. Farokhzad, Xiaoding Xu, Yanlan Liu, Aude Thiriot, Ulrich Von Andrian
  • Microvessel endothelial cell surface markers and uses thereof
    Patent number: 10307487
    Abstract: Disclosed herein are microvessel endothelial cell surface markers and methods, compositions, agents, and kits relating to those surface markers.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: June 4, 2019
    Assignees: President and Fellows of Harvard College, The Brigham and Women's Hospital
    Inventors: Ulrich H. von Andrian, Aude Thiriot, Omid Farokhzad, Jinjun Shi
  • Venule endothelial cell genes and uses thereof
    Patent number: 10206941
    Abstract: Disclosed herein are genes which are differentially expressed in venule endothelial cells (V-ECs) compared to non-venule endothelial cells (NV-ECs) and methods and compositions relating to those genes. Also disclosed herein are methods of modulating the venuleness of an endothelial cell or microvessel, methods of modulating leukocyte trafficking, methods of modulating inflammation, methods of targeting agents to tissues based on their ability to bind to surface markers expressed in a microvessel (e.g., venules and non-venules), methods of identifying the venuleness of endothelial cells or microvessels, methods of identifying agents that modulate the venuleness of endothelial cells or microvessels, methods of identifying agents that target microvessels, methods for treating diseases associated with leukocyte trafficking, methods for treating inflammatory diseases, and compositions and kits for use in the methods.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: February 19, 2019
    Assignees: President and Fellows of Harvard College, The Brigham and Women's Hospital, Inc.
    Inventors: Ulrich H. von Andrian, Aude Thiriot, Omid Farokhzad, Jinjun Shi
  • Amphiphile-Polymer Particles
    Publication number: 20170304213
    Abstract: This invention relates to amphiphile-polymer particles comprising obtaining a first solution comprising a water-insoluble polymer, a payload and a first amphiphile in a water-miscible solvent; mixing the first solution with an aqueous second solution to form an aqueous composition comprising a particle comprising a water-insoluble polymeric core comprising the water-insoluble polymer; the payload; and the first amphiphile.
    Type: Application
    Filed: October 23, 2015
    Publication date: October 26, 2017
    Inventors: Jinjun Shi, Xi Zhu, Omid C. Farokhzad, Xiaoding Xu, Yanlan Liu, Aude Thiriot, Ulrich Von Andrian
  • ENDOTHELIAL CELL GENES AND USES THEREOF
    Publication number: 20160354403
    Abstract: Disclosed herein are genes which are differentially expressed in venule endothelial cells (V-ECs) compared to non-venule endothelial cells (NV-ECs) and methods, compositions, kits, and agents relating to those genes.
    Type: Application
    Filed: July 9, 2014
    Publication date: December 8, 2016
    Inventors: Ulrich H. von Andrian, Aude Thiriot, Omid Farokhzad, Jinjun Shi
  • MICROVESSEL ENDOTHELIAL CELL SURFACE MARKERS AND USES THEREOF
    Publication number: 20160339113
    Abstract: Disclosed herein are microvessel endothelial cell surface markers and methods, compositions, agents, and kits relating to those surface markers.
    Type: Application
    Filed: July 9, 2014
    Publication date: November 24, 2016
    Inventors: UIrich H. VON ANDRIAN, Aude THIRIOT, Omid FAROKHZAD, Jinjun SHI