Patents by Inventor Audra DEVOTO

Audra DEVOTO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIPLEX EDITING WITH CAS ENZYMES
    Publication number: 20250075233
    Abstract: Described herein are methods, compositions, and systems for multiplex editing using Cas enzymes or editing of T-cells or related cells using Cas enzymes.
    Type: Application
    Filed: September 1, 2023
    Publication date: March 6, 2025
    Inventors: Brian C. THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Greg COST, Rebecca LAMOTHE, Diego ESPINOSA
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20250059568
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: August 27, 2024
    Publication date: February 20, 2025
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE
  • ENDONUCLEASE SYSTEMS
    Publication number: 20240409962
    Abstract: The present disclosure provides for endonuclease enzymes as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: May 10, 2024
    Publication date: December 12, 2024
    Inventors: Brian C. THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN
  • Class II, type V CRISPR systems
    Patent number: 12123014
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Grant
    Filed: April 18, 2023
    Date of Patent: October 22, 2024
    Assignee: Metagenomi, Inc.
    Inventors: Brian Thomas, Christopher Brown, Audra Devoto, Cristina Butterfield, Lisa Alexander, Daniela S. A. Goltsman, Justine Albers, Alan Brooks, Greg Cost, Morayma Temoche-Diaz, Cindy Castelle, Rebecca Lamothe
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20240344045
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: May 20, 2024
    Publication date: October 17, 2024
    Inventors: Brian C. THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU
  • CLASS II, TYPE II CRISPR SYSTEMS
    Publication number: 20240309356
    Abstract: The present disclosure provides for endonuclease enzymes as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: February 7, 2024
    Publication date: September 19, 2024
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN
  • ENDONUCLEASE SYSTEMS
    Publication number: 20240294948
    Abstract: The present disclosure provides for endonuclease enzymes as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: May 21, 2024
    Publication date: September 5, 2024
    Inventors: Brian C. THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Rebecca LAMOTHE
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20240218339
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: November 30, 2023
    Publication date: July 4, 2024
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN
  • Enzymes with RuvC domains
    Patent number: 12024727
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: July 2, 2024
    Assignee: Metagenomi, Inc.
    Inventors: Brian Thomas, Christopher Brown, Rose Kantor, Audra Devoto, Cristina Butterfield, Lisa Alexander, Daniela S. A. Goltsman, Jason Liu
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20240209332
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: November 7, 2022
    Publication date: June 27, 2024
    Inventors: Brian THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU, Rebecca LAMOTHE, Diego ESPINOSA, Meghan STORLIE, Greg COST
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20240200047
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: February 26, 2024
    Publication date: June 20, 2024
    Inventors: Brian C. THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU, Rebecca LAMOTHE, Diego ESPINOSA, Meghan STORLIE, Greg COST
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20240117330
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: June 15, 2023
    Publication date: April 11, 2024
    Inventors: Brian Thomas, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU
  • Class II, type II CRISPR systems
    Patent number: 11946039
    Abstract: The present disclosure provides for endonuclease enzymes as well as methods of using such enzymes or variants thereof.
    Type: Grant
    Filed: July 5, 2022
    Date of Patent: April 2, 2024
    Assignee: Metagenomi, Inc.
    Inventors: Brian Thomas, Christopher Brown, Audra Devoto, Cristina Butterfield, Lisa Alexander, Daniela S. A. Goltsman
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20240093239
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: April 18, 2023
    Publication date: March 21, 2024
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE
  • Class II, type V CRISPR systems
    Patent number: 11713471
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: August 1, 2023
    Assignee: METAGENOMI, INC.
    Inventors: Brian Thomas, Christopher Brown, Audra Devoto, Cristina Butterfield, Lisa Alexander, Daniela S. A. Goltsman, Justine Albers, Alan Brooks, Greg Cost, Morayma Temoche-Diaz, Cindy Castelle, Rebecca Lamothe
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20230227857
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: September 6, 2022
    Publication date: July 20, 2023
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine B. ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE
  • CLASS II, TYPE II CRISPR SYSTEMS
    Publication number: 20230051396
    Abstract: The present disclosure provides for endonuclease enzymes as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: July 5, 2022
    Publication date: February 16, 2023
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20220298494
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: February 14, 2020
    Publication date: September 22, 2022
    Inventors: Brian THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20220290187
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: March 28, 2022
    Publication date: September 15, 2022
    Inventors: Brian C. THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine B. ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE
  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20220220460
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: August 13, 2021
    Publication date: July 14, 2022
    Inventors: Brian THOMAS, Christopher BROWN, Rose KANTOR, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Jason LIU