Patents by Inventor Audrey CHANG

Audrey CHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VIRAL RESISTANT CELLS AND CULTURE SYSTEMS
    Publication number: 20190390241
    Abstract: Mammalian cell lines genetically engineered to be viral resistant, cell culture systems comprising agents that inhibit viral entry into or translocation within cells, and methods of using said cell lines and/or said cell culture systems to reduce or prevent viral contamination of biologic production systems.
    Type: Application
    Filed: January 24, 2018
    Publication date: December 26, 2019
    Inventors: Joaquina Mascarenhas, Audrey Chang, Nikolay Korokhov, David Onions, Henry George, Kevin J. Kayser
  • Viral resistant cells and uses thereof
    Patent number: 10377990
    Abstract: The present invention provides mammalian cell lines that have been genetically engineered causing such cell lines to be resistant to viral entry and/or propagation, and provides methods of using said cell lines to reduce or prevent viral contamination of biologic production systems.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: August 13, 2019
    Assignee: SIgma-Aldrich Co. LLC
    Inventors: Nan Lin, Joaquina Mascarenhas, Audrey Chang, David Onions, Henry George, Kevin Kayser
  • VIRAL RESISTANT CELLS AND USES THEREOF
    Publication number: 20160369240
    Abstract: The present invention provides mammalian cell lines that have been genetically engineered causing such cell lines to be resistant to viral entry and/or propagation, and provides methods of using said cell lines to reduce or prevent viral contamination of biologic production systems.
    Type: Application
    Filed: March 3, 2015
    Publication date: December 22, 2016
    Inventors: Nan LIN, Joaquina MASCARENHAS, Audrey CHANG, David ONIONS, Henry GEORGE, Kevin KAYSER
  • Methods and kits for detecting viral reverse transcriptase activity in a sample using an acidic pH or an elevated temperature
    Patent number: 5817457
    Abstract: Improved assay for the detection of viral reverse transcriptase activity using PCR conducts the reverse transcription reaction at an acidic pH or elevated temperature. The assay is useful in testing a wide variety of biological products and tissue samples.
    Type: Grant
    Filed: February 7, 1996
    Date of Patent: October 6, 1998
    Assignee: MA BioServices, Inc.
    Inventors: Robert E. Bird, Audrey Chang-Yeh