Abstract: Embodiments of the disclosure include processes for hydroconversion of hydrocarbon feedstocks in ebullated bed reactor systems. In particular, the systems comprise two or more ebullated bed reactors comprising catalyst particles, one or more inter-stage separation vessels, which are in fluid communication, and allow for the introduction of an additional solvent into the system between the final inter-stage separation vessel and the final ebullated bed reactor in the flow path. The processes include the addition of a solvent comprising water to an inter-stage liquid product prior to contact with the final ebullated bed reactor, which improves catalytic performance.