Patents by Inventor Audrey Minden

Audrey Minden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PAK5-related compositions and methods
    Patent number: 7482138
    Abstract: This invention provides nucleic acids encoding human PAK5-related proteins, and provides the encoded proteins. This invention also provides vectors, cells and compositions. Finally, this invention provides methods of inducing and inhibiting various cellular processes using the instant nucleic acids and proteins.
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: January 27, 2009
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Audrey Minden
  • PAK4-related antibodies
    Patent number: 7473766
    Abstract: This invention provides an isolated mammalian nucleic acid molecule encoding a PAK4 serine/threonine kinase. This invention provides an isolated nucleic acid molecule encoding a mutant homolog of the mammalian PAK4 serine/threonine kinase whose amino acid sequence is set forth in FIG. 1A (SEQ ID NO: 2). This invention provides a fusion protein comprising a PAK4 serine/threonine kinase or a fragment thereof and a second peptide. This invention provides a purified mammalian PAK4 serine/threonine kinase. This invention provides a protein comprising substantially the amino acid sequence set forth in FIG. 1A. This invention provides a monoclonal antibody directed to an epitope of a PAK4 serine/threonine kinase. This invention provides a method of inhibiting PAK4 function comprising administering a ligand comprising an amino acid domain which binds to a GTP binding protein so as to inhibit binding of the GTP binding protein to PAK4.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: January 6, 2009
    Assignee: The Trustees of Columbia University in the city of New York
    Inventor: Audrey Minden
  • PAK4 - related antibodies
    Publication number: 20040091992
    Abstract: This invention provides an isolated mammalian nucleic acid molecule encoding a PAK4 serine/threonine kinase. This invention provides an isolated nucleic acid molecule encoding a mutant homolog of the mammalian PAK4 serine/threonine kinase whose amino acid sequence is set forth in FIG. 1A (SEQ ID NO: 2). This invention provides a fusion protein comprising a PAK4 serine/threonine kinase or a fragment thereof and a second peptide. This invention provides a purified mammalian PAK4 serine/threonine kinase. This invention provides a protein comprising substantially the amino acid sequence set forth in FIG. 1A. This invention provides a monoclonal antibody directed to an epitope of a PAK4 serine/threonine kinase. This invention provides a method of inhibiting PAK4 function comprising administering a ligand comprising an amino acid domain which binds to a GTP binding protein so as to inhibit binding of the GTP binding protein to PAK4.
    Type: Application
    Filed: October 24, 2003
    Publication date: May 13, 2004
    Applicant: The Trustees of Columbia University in the City of New York
    Inventor: Audrey Minden
  • PAK4, a novel gene encoding a serine/threonine kinase
    Patent number: 6667168
    Abstract: This invention provides an isolated mammalian nucleic acid molecule encoding a PAK4 serine/threonine kinase. This invention provides an isolated nucleic acid molecule encoding a mutant homolog of the mammalian PAK4 serine/threonine kinase whose amino acid sequence is set forth in FIG. 1A (SEQ ID NO: 2). This invention provides a fusion protein comprising a PAK4 serine/threonine kinase or a fragment thereof and a second peptide. This invention provides a purified mammalian PAK4 serine/threonine kinase. This invention provides a protein comprising substantially the amino acid sequence set forth in FIG. 1A. This invention provides a monoclonal antibody directed to an epitope of a PAK4 serine/threonine kinase. This invention provides a method of inhibiting PAK4 function comprising administering a ligand comprising an amino acid domain which binds to a GTP binding protein so as to inhibit binding of the GTP binding protein to PAK4.
    Type: Grant
    Filed: November 21, 2000
    Date of Patent: December 23, 2003
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Audrey Minden
  • PAK5-related compositions and methods
    Publication number: 20030124107
    Abstract: This invention provides nucleic acids encoding mammalian PAK5-related proteins, and provides the encoded proteins. This invention also provides vectors, cells and compositions. Finally, this invention provides methods of inducing and inhibiting various cellular processes using the instant nucleic acids and proteins.
    Type: Application
    Filed: December 27, 2002
    Publication date: July 3, 2003
    Inventor: Audrey Minden
  • PAK4, a novel gene encoding a serine/threonine kinase
    Patent number: 6013500
    Abstract: This invention provides an isolated mammalian nucleic acid molecule encoding a PAK4 serine/threonine kinase. This invention provides an isolated nucleic acid molecule encoding a mutant homolog of the mammalian PAK4 serine/threonine kinase whose amino acid sequence is set forth in FIG. 1A (SEQ ID NO: 2). This invention provides a fusion protein comprising a PAK4 serine/threonine kinase or a fragment thereof and a second peptide. This invention provides a purified mammalian PAK4 serine/threonine kinase. This invention provides a protein comprising substantially the amino acid sequence set forth in FIG. 1A. This invention provides a monoclonal antibody directed to an epitope of a PAK4 serine/threonine kinase. This invention provides a method of inhibiting PAK4 function comprising administering a ligand comprising an amino acid domain which binds to a GTP binding protein so as to inhibit binding of the GTP binding protein to PAK4.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: January 11, 2000
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Audrey Minden