Patents by Inventor August J. Sick

August J. Sick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5286485
    Abstract: The subject disclosure concerns Bacillus thuringiensis strains which can be used to control lepidopteran pests. The strains were previously known to control coleopteran pests. The discovery of lepidopteran activity was totally unexpected.These B.t. strains can be formulated using standard lepidopteran formulation procedures. Means of administration are also standard.The genes encoding lepidopteran-active toxins can be isolated from the B.t. isolates and used to transform other microbes for use to control lepidopteran pests.
    Type: Grant
    Filed: September 12, 1991
    Date of Patent: February 15, 1994
    Assignee: Mycogen Corporation
    Inventors: Kendrick A. Uyeda, Luis Foncerrada, Jewel M. Payne, Kenneth E. Narva, George E. Schwab, Gregory A. Bradfisch, August J. Sick
  • Patent number: 5281530
    Abstract: Nematicidal .delta.-endotoxin encoding genes have been cloned from a novel Bacillus thuringiensis isolate known as B.t. PS17. These novel genes, designated B.t. PS17a, B.t. PS17b, Bt. PS17d, and B.t. PS17e, can be transferred to various microbial and plant hosts via known techniques. In the microbial or plant host, one or more of the genes of the invention can be used to express the novel nematicidal toxins to control susceptible nematodes.
    Type: Grant
    Filed: July 24, 1990
    Date of Patent: January 25, 1994
    Assignee: Mycogen Corporation
    Inventors: August J. Sick, George E. Schwab, Jewel M. Payne
  • Patent number: 5277905
    Abstract: The subject invention concerns a novel microbe and gene encoding a novel toxin protein with activity against insect pests of the order Coleoptera. Pests in the order Coleoptera do heavy damage to crops, e.g., corn. The novel Bacillus thuringiensis microbe of the invention is referred to as B.t. PS50C. The spores or crystals of this microbe, or mutants thereof, are useful to control coleopteran pests in various environments. The novel gene of the invention can be used to transform various hosts wherein the novel toxic protein can be expressed.
    Type: Grant
    Filed: January 16, 1991
    Date of Patent: January 11, 1994
    Assignee: Mycogen Corporation
    Inventors: Luis Foncerrada, August J. Sick, Jewel M. Payne
  • Patent number: 5262399
    Abstract: Methods and compositions for the control of flukes are described. Specifically, Bacillus thuringiensis (B.t.) isolates having flukicidal activity are disclosed. Also described are recombinant hosts which express B.t. genes coding for flukicidal toxins. The B.t. isolates and recombinant proteins are shown to be useful in a method for controlling flukes including the liver fluke.
    Type: Grant
    Filed: March 27, 1991
    Date of Patent: November 16, 1993
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, August J. Sick, George E. Schwab, Kenneth E. Narva, Jewel M. Payne
  • Patent number: 5246852
    Abstract: Novel Bacillus thuringiensis genes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-active B. thuringiensis microbes. The DNA encoding the B. thuringiensis toxins can be used to transform various prokaryotic and eukaryotic microbes to express the B. thuringiensis toxins. These recombinant microbes can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: June 12, 1991
    Date of Patent: September 21, 1993
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick
  • Patent number: 5206166
    Abstract: Novel Bacillus thuringiensis genes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-active B. thuringiensis microbes. The DNA encoding the B. thuringiensis toxins can be used to transform various prokaryotic and eukaryotic microbes to express the B. thuringiensis toxins. These recombinant microbes can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: June 25, 1992
    Date of Patent: April 27, 1993
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick
  • Patent number: 5204237
    Abstract: This invention concerns novel gene probes which can be used to identify DNA from Bacillus thuringiensis microbes which encode insecticidally-active protein endotoxins. The invention probes greatly facilitate the search for useful microbes hosting genes which encode insecticidally-active toxins.
    Type: Grant
    Filed: July 26, 1991
    Date of Patent: April 20, 1993
    Assignee: Mycogen Corporation
    Inventors: Frank H. Gaertner, August J. Sick, George E. Schwab
  • Patent number: 5188960
    Abstract: Novel Bacillus thuringiensis genes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-active B. thuringiensis microbes. The DNA encoding the B. thuringiensis toxins can be used to transform various prokaryotic and eukaryotic microbes to express the B. thuringiensis toxins. These recombinant microbes can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: December 14, 1989
    Date of Patent: February 23, 1993
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick
  • Patent number: 5169629
    Abstract: A novel B.t. isolate with activity against lepidopteran insects is disclosed. This isolate is highly active agaist the beet armyworm. A gene from this isolate has been cloned. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: November 1, 1988
    Date of Patent: December 8, 1992
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick, Mark Thompson
  • Patent number: 5164180
    Abstract: Novel Bacillus thuringiensis genes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-active B. thuringiensis microbes. The DNA encoding the B. thuringiensis toxins can be used to transform various prokaryotic and eukaryotic microbes to express the B. thuringiensis toxins. These recombinant microbes can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: December 14, 1989
    Date of Patent: November 17, 1992
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick
  • Patent number: 5135867
    Abstract: A novel B.t. isolate with activity against lepidopteran insects is disclosed. This isolate is highly active against the beet armyworm. A gene from this isolate has been cloned. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: November 16, 1990
    Date of Patent: August 4, 1992
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick, Mark Thompson
  • Patent number: 5133962
    Abstract: A novel B.t. toxin gene encoding a protein toxic to coleopteran insects has been cloned from a novel coleopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control coleopteran insects in various environments.
    Type: Grant
    Filed: November 9, 1989
    Date of Patent: July 28, 1992
    Assignee: Mycogen Corporation
    Inventors: August J. Sick, Thomas E. Gilroy
  • Patent number: 5126133
    Abstract: Novel Bacillus thuringiensis genes encoding toxins which are active against lepidopteran insects have been cloned from novel lepidopteran-active B. thuringiensis microbes. The DNA encoding the B. thuringiensis toxins can be used to transform various prokaryotic and eukaryotic microbes to express the B. thuringiensis toxins. These recombinant microbes can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: June 27, 1989
    Date of Patent: June 30, 1992
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick
  • Patent number: 5104974
    Abstract: A novel B.t. toxin gene encoding a protein toxic to coleopteran insects has been cloned from a novel coleopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control coleopteran insects in various environments.
    Type: Grant
    Filed: November 9, 1989
    Date of Patent: April 14, 1992
    Assignee: Mycogen Corporation
    Inventors: August J. Sick, Thomas E. Gilroy
  • Patent number: 5064648
    Abstract: The subject invention concerns the use of a novel and useful bioinsecticide against the lesser mealworm (Alphitobius diaperinus). The lesser mealworm is a devasting pest in the poultry industry. The bioinsecticide of the subject invention is a novel B. thuringiensis microbe referred to a B.t. PS43F, or mutants thereof. The spores or toxin crystals of this microbe are useful to control the lesser mealworm in various environments.
    Type: Grant
    Filed: September 11, 1990
    Date of Patent: November 12, 1991
    Assignee: Mycogen Corporation
    Inventors: Leslie A. Hickle, Gregory A. Bradfisch, August J. Sick
  • Patent number: 5045469
    Abstract: A novel B.t. toxin gene toxic to lepidopteran insects has been cloned from a novel lepidopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: October 27, 1988
    Date of Patent: September 3, 1991
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick
  • Patent number: 5039523
    Abstract: A novel B.t. toxin gene encoding a protein toxic to lepidopteran insects has been cloned from a novel lepidopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control lepidopteran insects in various environments.
    Type: Grant
    Filed: November 13, 1990
    Date of Patent: August 13, 1991
    Assignee: Mycogen Corporation
    Inventors: Jewel Payne, August J. Sick
  • Patent number: 4996155
    Abstract: A novel B.t. toxin gene encoding a protein toxic to coleopteran insects has been cloned from a novel coleopteran-active B. thuringiensis microbe. The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control coleopteran insects in various environments.
    Type: Grant
    Filed: March 4, 1988
    Date of Patent: February 26, 1991
    Assignee: Mycogen Corporation
    Inventors: August J. Sick, Thomas E. Gilroy