Patents by Inventor August Lodewijk Verbruggen

August Lodewijk Verbruggen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxyethylated cyclodextrin polysulfates useful as medicaments
    Patent number: 8466278
    Abstract: This invention relates to novel ?-cyclodextrin polysulfate compounds comprising from one to three 2-carboxyethyl substituents, and at least two sulfates groups per glucopyranose unit, which are useful as active ingredients for the treatment and/or prophylaxis of degenerative joint diseases, osteoarthritis, articular rheumatism, arthrosis or degenerative arthritis, or for the treatment of heparin-induced thrombocytopenia, or for cartilage repair or connective tissue repair.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: June 18, 2013
    Assignee: Arcarios B.V.
    Inventors: Dirk Elewaut, August Lodewijk Verbruggen
  • Carboxyethylated Cyclodextrin Polysulfates Useful As Medicaments
    Publication number: 20110172182
    Abstract: This invention relates to novel ?-cyclodextrin polysulfate compounds comprising from one to three 2-carboxyethyl substituents, and at least two sulfates groups per glucopyranose unit, which are useful as active ingredients for the treatment and/or prophylaxis of degenerative joint diseases, osteoarthritis, articular rheumatism, arthrosis or degenerative arthritis, or for the treatment of heparin-induced thrombocytopenia, or for cartilage repair or connective tissue repair.
    Type: Application
    Filed: September 22, 2009
    Publication date: July 14, 2011
    Applicant: ARCARIOS B.V.
    Inventors: Dirk Elewaut, August Lodewijk Verbruggen
  • Therapeutic use for a group of sulphated polysaccharides
    Patent number: 7816329
    Abstract: The present invention relates to the use of a sulphated polysaccharide in acid form or as a physiologically acceptable salt thereof, selected from the group constituting of inulin sulphate, gellan sulphate, pullulan sulphate, curdlan sulphate, alginiq acid sulphate, laminarin sulphate, and pectin sulphate, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal. Preferably, the sulphated polysaccharide is inulin sulphate, most preferably inulin polysulphate sodium salt. The present invention also relates to the use of a sulphated oligosaccharide derived from a polysaccharide selected from the group consisting of inulin, gellan, pullulan, curdlan, alginic acid, laminarin, and pectin, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: October 19, 2010
    Assignee: Bioiberica, S.A.
    Inventors: Francisco Javier Vila Pahi, Josep Escaich Ferrer, August Lodewijk Verbruggen, Josep Verges Milano, Ramon Ruhi Roura, Carlos Raul Alaez Verson
  • Therapeutic Use for a Group of Sulphated Polysaccharides
    Publication number: 20080051350
    Abstract: The present invention relates to the use of a sulphated polysaccharide in acid form or as a physiologically acceptable salt thereof, selected from the group consisting of inulin sulphate, gellan sulphate, pullulan sulphate, curdlan sulphate, alginiq acid sulphate, laminarin sulphate, and pectin sulphate, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal. Preferably, the sulphated polysaccharide is inulin sulphate, most preferably inulin polysulphate sodium salt. The present invention also relates to the use of a sulphated oligosaccharide derived from a polysaccharide selected from the group consisting of inulin, gellan, pullulan, curdlan, alginic acid, laminarin, and pectin, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal.
    Type: Application
    Filed: February 11, 2005
    Publication date: February 28, 2008
    Applicant: Bioiberica, S.A.
    Inventors: Francisco Javier Vila Pahi, Josep Escaich Ferrer, August Lodewijk Verbruggen, Josep Verges Milano, Ramon Ruhi Roura, Carlos Raul Alaez Verson
  • Use of polysulphated cyclodextrins for treating osteoarthritis
    Patent number: 6930098
    Abstract: The present invention relates to the method of using polysulphated cyclodextrins or addition salts thereof for use in the treatment of arthrosis, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: July 12, 2001
    Date of Patent: August 16, 2005
    Assignee: Universiteit Gent
    Inventors: Eric Maximilien Veys, August Lodewijk Verbruggen
  • Use of polysulphated cyclodextrins for treating osteoarthritis
    Publication number: 20030109493
    Abstract: The present invention relates to the use of polysulphated cyclodextrins or addition salts thereof in obtaining pharmaceutical compositions for use in the treatment of arthrosis.
    Type: Application
    Filed: January 15, 2003
    Publication date: June 12, 2003
    Inventors: Eric Maximilien Veys, August Lodewijk Verbruggen