Patents by Inventor Augustín Bienvendo Lage Davila

Augustín Bienvendo Lage Davila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunomodulatory interleukin-2 polypeptides and methods of treating melanoma
    Patent number: 8759486
    Abstract: The present invention relates generally to polypeptides whose primary sequence has high sequence homology with human interleukin 2 (IL-2) with some punctual mutations in the sequence of native IL-2. The polypeptides of the present invention have an immunomodulatory effect on the immune system, which is selective/preferential on regulatory T cells. The present invention also relates to specific polypeptides whose amino acid sequence is disclosed herein. In another aspect the present invention relates to pharmaceutical compositions comprising as active ingredient the polypeptides disclosed. Finally, the present invention relates to the therapeutic use of the polypeptides and pharmaceutical compositions disclosed due to their immune modulating effect on diseases such as cancer and chronic infectious diseases.
    Type: Grant
    Filed: November 26, 2010
    Date of Patent: June 24, 2014
    Assignee: Centro de Inmunologia Molecular
    Inventors: Kalet León Monzón, Tania Carmenate Portilla, Karina García Martínez, Augustín Bienvendo Lage Davila, Samuel Pérez Rodríguez, Diamile González Roche, Gabriel Márquez Perera