Patents by Inventor August Schubiger

August Schubiger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the linkage of bifunctional chelating agents and (radioactive) transition metal complexes to proteins and peptides
    Publication number: 20070184537
    Abstract: The present invention relates to a method for radioactive labeling of a protein or peptide, by providing a protein or peptide having at least one glutamine or lysine residue; adding a metal chelating agent having at least one lysine or glutamine residue, respectively, which metal chelating agent is optionally complexed with a radioactive or paramagnetic metal; reacting the protein or peptide and metal chelating agent in the presence of a transglutaminase to obtain a protein or peptide with a metal chelating group covalently bound thereto, and optionally complexing the metal chelating group with a radioactive or paramagnetic metal. The invention also relates to proteins and peptides thus labeled and to proteins and peptides that have been coupled to a metal chelating agent but not yet labeled.
    Type: Application
    Filed: June 2, 2004
    Publication date: August 9, 2007
    Applicant: Paul Scherrer Institut
    Inventors: Roger Schibli, Albert Stichelberger, Robert Waibel, August Schubiger