Patents by Inventor August Wilhelm Wahlefeld

August Wilhelm Wahlefeld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • .gamma.-Glutamyl-4-nitroanilide compounds
    Patent number: 4049702
    Abstract: .gamma.-Glutamyl-4-nitroanilide compounds of the formula ##STR1## wherein R is a .gamma.-glutamyl radical and X is an acid group, and salts of such compounds, are used to determine .gamma.-glutamyl-transpeptidase by contacting a sample suspected of containing .gamma.-glutamyltranspeptidase with said compound and glycylglycine and determining the liberation of the resulting p-nitro-aniline compound as a measure of the .gamma.-glutamyltranspeptidase activity initially present in the sample.
    Type: Grant
    Filed: June 23, 1975
    Date of Patent: September 20, 1977
    Assignee: Boehringer Mannheim G.m.b.H.
    Inventors: Erich Bernt, Wolfgang Gruber, Erich Haid, Fritz Stahler, August Wilhelm Wahlefeld, Gunter Weimann
  • Analytical enzymatic determination
    Patent number: 4019961
    Abstract: An analytical process for enzymatic determination of a substrate in biological fluids. The fluid sample is reacted first in the absence of the specific kinase but in the presence of an NADH -- regenerating enzymatic system with the reagents needed for the reaction sequence; then the enzymes are separated from the reaction solution, and thereafter the necessary enzymes are added to the filtrate and NADH consumption is measured.The method is very accurate, economical in requiring less enzymes and only one measurement is necessary.
    Type: Grant
    Filed: March 10, 1975
    Date of Patent: April 26, 1977
    Assignee: Boehringer Mannheim G.m.b.H.
    Inventors: Sigmar Klose, August Wilhelm Wahlefeld, Alexander Hagen
  • .gamma.-GLUTAMYL-4-NITROANILIDE COMPOUNDS AND THEIR USE IN DETERMINING .gamma.-GLUTAMYL TRANSPEPTIDASE
    Patent number: 3986931
    Abstract: .gamma.-Glutamyl-4-nitroanilide compounds of the formula ##SPC1##Wherein R is a .gamma.-glutamyl radical and X is an acid group, and salts of such compounds, are used to determine .gamma.-glutamyltranspeptidase by contacting a sample suspected of containing .gamma.-glutamyltranspeptidase with said compound and glycyl-glycine and determining the liberation of the resulting p-nitroaniline compound as a measure of the .gamma.-glutamyltranspeptidase activity initially present in the sample.
    Type: Grant
    Filed: August 4, 1975
    Date of Patent: October 19, 1976
    Assignee: Boehringer Mannheim G.m.b.H.
    Inventors: Erich Bernt, Wolfgang Gruber, Erich Haid, Fritz Stahler, August Wilhelm Wahlefeld, Gunter Weimann
  • .gamma.-Glutamyl-4-nitroanilide compounds
    Patent number: 3979447
    Abstract: .gamma.-Glutamyl-4-nitroanilide compounds of the formula ##SPC1##Wherein R is a .gamma.-glutamyl radical and X is an acid group, and salts of such compounds, are used to determine .gamma.-glutamyltranspeptidase by contacting a sample suspected of containing .gamma.-glutamyltranspeptidase with said compound and glycylglycine and determining the liberation of the resulting p-nitroaniline compound as a measure of the .gamma.-glutamyltranspeptidase activity initially present in the sample.
    Type: Grant
    Filed: November 27, 1973
    Date of Patent: September 7, 1976
    Assignee: Boehringer Mannheim G.m.b.H.
    Inventors: Erich Bernt, Wolfgang Gruber, Erich Haid, Fritz Stahler, August Wilhelm Wahlefeld, Gunter Weimann