Patents by Inventor Augustine Kong

Augustine Kong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetic markers associated with risk of diabetes mellitus
    Patent number: 8796182
    Abstract: The invention relates to variants that predispose to risk of type 2 diabetes, basal cell carcinoma and breast cancer. It has been discovered that certain genetic variants confer risk of these diseases when inherited from one parent, but not the other. The invention provides methods of disease management, including diagnostic methods, utilizing such parental origin effects.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: August 5, 2014
    Assignee: deCODE Genetics ehf.
    Inventors: Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Daniel Gudbjartsson, Gisli Masson, Augustine Kong
  • GENETIC MARKERS ASSOCIATED WITH RISK OF DIABETES MELLITUS
    Publication number: 20120220477
    Abstract: The invention relates to variants that predispose to risk of type 2 diabetes, basal cell carcinoma and breast cancer. It has been discovered that certain genetic variants confer risk of these diseases when inherited from one parent, but not the other. The invention provides methods of disease management, including diagnostic methods, utilizing such parental origin effects.
    Type: Application
    Filed: July 9, 2010
    Publication date: August 30, 2012
    Applicant: deCODE Genetics ehf.
    Inventors: Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Daniel Gudbjartsson, Gisli Masson, Augustine Kong
  • CANCER SUSCEPTIBILITY VARIANTS ON CHR8Q24.21
    Publication number: 20100129799
    Abstract: A region on chromosome 8q24.21 has been demonstrated to play a major role in particular forms of cancer. It has been discovered that certain markers and haplotypes are indicative of a susceptibility to particular cancers, including prostate cancer. Diagnostic applications for identifying a susceptibility to cancer using these markers and haplotypes are described.
    Type: Application
    Filed: October 26, 2007
    Publication date: May 27, 2010
    Applicant: deCODE genetics ehf.
    Inventors: Júlíus Guômundsson, Patric Sulem, Augustine Kong, Andrei Manulescu, Laufey Amundadottir
  • Inversion on chromosome 8p23 is a risk factor for anxiety disorders, depression and bipolar disorders
    Publication number: 20070111209
    Abstract: An association between psychiatric disorders and disorders comorbid with psychiatric disorders, and genetic markers in the 8p23 genomic region is described. Markers are also provided to diagnose or detect a susceptibility to disorders comorbid with panic disorder and independently of comorbidity with panic disorder. Methods and surrogate markers for detecting the orientation of the Inv8p23 inversion fragment, thereby diagnosing psychiatric disorders or comorbid disorders or a susceptibility to psychiatric disorders or comorbid disorders, are also disclosed. The methods described herein are also useful for determining responsiveness of drugs useful for treating psychiatric disorders.
    Type: Application
    Filed: September 17, 2004
    Publication date: May 17, 2007
    Inventors: Soley Bjornsdottir, Augustine Kong, Thorgeir Thorgeirsson
  • Methods for diagnosing and characterizing breast cancer and susceptibility to breast cancer
    Publication number: 20070092900
    Abstract: Methods and kits for diagnosing and characterizing breast cancer or a susceptibility to breast cancer are described herein. Diagnosis and characterization methods comprise detecting the BARD1 Cys557Ser allele or a haplotype comprising the BARD1 Cys557Ser allele in patients with or without a familial predisposition to cancer. The methods described herein further allow for the characterization of a tumor as invasive or non-invasive, and allow for the prediction of whether a patient who has a primary tumor is likely to develop a second primary tumor.
    Type: Application
    Filed: August 31, 2006
    Publication date: April 26, 2007
    Inventors: Simon Stacey, Patrick Sulem, Unnur Thorsteinsdottir, Augustine Kong