Patents by Inventor Augustine M. K. Choi

Augustine M. K. Choi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of mitochondrial iron chelators for treatment of chronic obstructive pulmonary disease
    Patent number: 10905682
    Abstract: A method for treating one or more symptoms of COPD comprising administering to an in need of treatment a therapeutically effect amount of one or more mitochondrial iron chelators. The mitochondrial iron chelator can be deferiprone. Compostions comprising mitochondrial iron chelators suitable for administration are also disclosed.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: February 2, 2021
    Assignee: Cornell University
    Inventors: Augustine M. K. Choi, Suzanne M. Cloonan
  • USE OF MITOCHONDRIAL IRON CHELATORS FOR TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
    Publication number: 20180360815
    Abstract: A method for treating one or more symptoms of COPD comprising administering to an in need of treatment a therapeutically effect amount of one or more mitochondrial iron chelators. The mitochondrial iron chelator can be deferiprone. Compostions comprising mitochondrial iron chelators suitable for administration are also disclosed.
    Type: Application
    Filed: December 1, 2016
    Publication date: December 20, 2018
    Inventors: Augustine M.K. CHOI, Suzanne M. CLOONAN
  • Methods of treating hepatitis
    Patent number: 9522163
    Abstract: The present invention relates to a method of treating hepatitis in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: December 20, 2016
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, Yale University
    Inventors: Leo E. Otterbein, Augustine M. K. Choi, Brian Scott Zuckerbraun
  • METHODS OF TREATING HEPATITIS
    Publication number: 20140141103
    Abstract: The present invention relates to a method of treating hepatitis in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Application
    Filed: December 2, 2013
    Publication date: May 22, 2014
    Inventors: Leo E. Otterbein, Augustine M. K. Choi, Brian Scott Zuckerbraun
  • Method of Treating Hepatitis
    Publication number: 20120276220
    Abstract: The present invention relates to a method of treating hepatitis in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Application
    Filed: July 9, 2012
    Publication date: November 1, 2012
    Applicants: Yale University, University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Leo E. Otterbein, Augustine M. K. Choi, Brian Zuckerbraun
  • Methods of treating ileus
    Patent number: 7687079
    Abstract: The present invention relates to a method of treating ileus in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Grant
    Filed: February 21, 2003
    Date of Patent: March 30, 2010
    Assignees: University of Pittsburgh of the Commonwealth System of Higher Education Yale University, Yale University
    Inventors: Leo E. Otterbein, Augustine M. K. Choi, Beverley A. Moore, Anthony J. Bauer
  • Carbon monoxide as a biomarker and therapeutic agent
    Patent number: 7678390
    Abstract: The present invention relates to the use of carbon monoxide (CO) as a biomarker and therapeutic agent of heart, lung, liver, spleen, brain, skin and kidney diseases and other conditions and disease states including, for example, asthma, emphysema, bronchitis, adult respiratory distress syndrome, sepsis, cystic fibrosis, pneumonia, interstitial lung diseases, idiopathic pulmonary diseases, other lung diseases including primary pulmonary hypertension, secondary pulmonary hypertension, cancers, including lung, larynx and throat cancer, arthritis, wound healing, Parkinson's disease, Alzheimer's disease, peripheral vascular disease and pulmonary vascular thrombotic diseases such as pulmonary embolism. CO may be used to provide anti-inflammatory relief in patients suffering from oxidative stress and other conditions especially including sepsis and septic shock.
    Type: Grant
    Filed: January 15, 2002
    Date of Patent: March 16, 2010
    Assignees: Yale University, John Hopkins University
    Inventors: Augustine M. K. Choi, Leo E. Otterbein
  • METHODS OF TREATING VASCULAR DISEASE
    Publication number: 20080167609
    Abstract: The present invention relates to a method of treating patients suffering from, or at risk for, intimal hyperplasia and/or arteriosclerosis. The treatment includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Application
    Filed: March 18, 2008
    Publication date: July 10, 2008
    Inventors: Leo E. Otterbein, Augustine M. K. Choi, Fritz H. Bach, Brian Zuckerbraun
  • Methods of treating vascular disease
    Patent number: 7364757
    Abstract: The present invention relates to a method of treating patients suffering from, or at risk for, intimal hyperplasia and/or arteriosclerosis. The treatment includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: April 29, 2008
    Assignees: University of Pittsburgh of the Commonwealth System of Higher Education, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Leo E. Otterbein, Augustine M. K. Choi, Fritz H. Bach, Brian Zuckerbraun
  • Methods of treating angiogenesis, tumor growth, and metastasis
    Publication number: 20040258772
    Abstract: The present invention relates to a method of treating cancer or unwanted angiogenesis in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Application
    Filed: June 5, 2003
    Publication date: December 23, 2004
    Inventors: Leo E. Otterbein, Augustine M. K. Choi
  • Treatment for hemorrhagic shock
    Publication number: 20040228930
    Abstract: The present invention relates to methods and compositions of treating patients suffering from, or at risk for, hemorrhagic shock. The treatment includes administering to the patient a pharmaceutical composition that includes carbon monoxide.
    Type: Application
    Filed: September 30, 2003
    Publication date: November 18, 2004
    Inventors: Timothy R. Billiar, Augustine M.K. Choi, Carol A. McCloskey, Leo E. Otterbein, Brian Zuckerbraun
  • Methods of treating hepatitis
    Publication number: 20040052866
    Abstract: The present invention relates to a method of treating hepatitis in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Application
    Filed: May 16, 2003
    Publication date: March 18, 2004
    Inventors: Leo E. Otterbein, Augustine M. K. Choi, Brian Zuckerbraun
  • Methods of treating ileus
    Publication number: 20030219497
    Abstract: The present invention relates to a method of treating ileus in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Application
    Filed: February 21, 2003
    Publication date: November 27, 2003
    Inventors: Leo E. Otterbein, Augustine M. K. Choi, Beverley A. Moore, Anthony J. Bauer
  • Methods of treating vascular disease
    Publication number: 20030219496
    Abstract: The present invention relates to a method of treating patients suffering from, or at risk for, intimal hyperplasia and/or arteriosclerosis. The treatment includes administering a pharmaceutical composition that includes carbon monoxide to the patient.
    Type: Application
    Filed: February 13, 2003
    Publication date: November 27, 2003
    Inventors: Leo E. Otterbein, Augustine M. K. Choi, Fritz H. Bach, Brian Zuckerbraun