Patents by Inventor Augustinus A.M.S. Van Dongen

Augustinus A.M.S. Van Dongen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing cell targeting conjugates, and the complexes obtained
    Patent number: 10668162
    Abstract: A first aspect of the disclosure relates to a method for preparing cell-targeting conjugates by coupling at least one functional moiety, such as a therapeutic compound, diagnostic compound or chelating agent to a targeting moiety. A second aspect of this disclosure relates to the cell-targeting conjugates obtainable with this method. A third aspect of the disclosure described herein relates to pharmaceutical compositions comprising the cell-targeting conjugates.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: June 2, 2020
    Assignee: LinXis B.V.
    Inventors: Hendrik Jan Houthoff, Augustinus A. M. S. Van Dongen, Robbert Jan Kok, Dennis Christian Johannes Waalboer, Sytze Jan Buwalda, Niels Jurriaan Sijbrandi
  • Method for removing weakly bound functional moieties from cell targeting conjugates
    Patent number: 10668168
    Abstract: This disclosure describes a method for preparing stable cell targeting conjugates. A further aspect of this disclosure relates to the stable cell targeting conjugates obtainable by the method and to pharmaceutical compositions comprising these stable cell targeting conjugates. A last aspect of this disclosure relates to the use of these conjugates and pharmaceutical compositions as a medicament.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: June 2, 2020
    Assignee: LinXis B.V.
    Inventors: Augustinus A. M. S. Van Dongen, Niels Jurriaan Sijbrandi, Dennis Christian Johannes Waalboer, Hendrik Jan Houthoff
  • METHOD FOR REMOVING WEAKLY BOUND FUNCTIONAL MOIETIES FROM CELL TARGETING CONJUGATES
    Publication number: 20180055947
    Abstract: This disclosure describes a method for preparing stable cell targeting conjugates. A further aspect of this disclosure relates to the stable cell targeting conjugates obtainable by the method and to pharmaceutical compositions comprising these stable cell targeting conjugates. A last aspect of this disclosure relates to the use of these conjugates and pharmaceutical compositions as a medicament.
    Type: Application
    Filed: March 9, 2016
    Publication date: March 1, 2018
    Inventors: Augustinus A. M. S. Van Dongen, Niels Jurriaan Sijbrandi, Dennis Christian Johannes Waalboer, Hendrik Jan Houthoff
  • METHOD FOR PREPARING CELL TARGETING CONJUGATES, AND THE COMPLEXES OBTAINED
    Publication number: 20140377174
    Abstract: A first aspect of the disclosure relates to a method for preparing cell-targeting conjugates by coupling at least one functional moiety, such as a therapeutic compound, diagnostic compound or chelating agent to a targeting moiety. A second aspect of this disclosure relates to the cell-targeting conjugates obtainable with this method. A third aspect of the disclosure described herein relates to pharmaceutical compositions comprising the cell-targeting conjugates.
    Type: Application
    Filed: January 4, 2013
    Publication date: December 25, 2014
    Inventors: Hendrik Jan Houthoff, Augustinus A.M.S. Van Dongen, Robbert Jan Kok, Dennis Christian Johannes Waalboer, Sytze Jan Buwalda, Niels Jurriaan Sijbrandi