Abstract: A system and method for optical lymph node mapping. The system is useful for guiding sentinel lymph node biopsy surgeries. A contrast agent that includes a fluorescent dye is injected near the site of a malignancy. The contrast agent drains into the lymphatic system, collecting in a sentinel node or nodes. The system utilizes one or more low-power continuous-wave lasers or light-emitting diodes modulated with a digital code sequence to probe the tissue suspected of containing the sentinel node. When the light is incident near the sentinel node, it will excite fluorescence from the dye. A portion of the scattered fluorescent light is captured with one or more photo-detectors. A correlation of the photo-detector signal and the digital code sequence is calculated to produce an estimate of the distribution of flight times for photons traveling from a given source to a given detector.

Abstract: A system and method for measuring photons utilizing a low-power light source modulated with a code sequence to interrogate a sample of interest. Preferably a portion of the scattered light from the sample is detected by a photo-detector. A correlation of the photo-detector signal and the code sequence produces an estimate of the distribution of flight times for photons traveling from the source to the detector.

Abstract: A system and method for measuring photons utilizing a low-power light source modulated with a code sequence to interrogate a sample of interest. Preferably a portion of the scattered light from the sample is detected by a photo-detector. A correlation of the photo-detector signal and the code sequence produces an estimate of the distribution of flight times for photons traveling from the source to the detector.

Abstract: An image reconstruction system that can generate an accurate image representation of structure and regions within an object is disclosed. An aspect of the invention comprises a processor that is configured to receive x-ray transmissive information for an object to generate image pixel information for a plurality of depths within the object. The display image comprises selected image pixel information corresponding to image pixels at a plurality of depths within the object.

Abstract: A dynamic data distribution network (12) for use with a software package (10), which includes modules (14, 16, and 18) that produce data and modules (20, 22, 24, and 26) that consume data. The network includes source files (30) and sink files (32). Each data-consuming module contains one or more sink files, each of which serves as a buffer for one type of data used by the module. Each source file serves as a buffer for one type of data that is generated by a data-producing module. Each source file also contains a sink link table (40) that identifies the individual sink files, which serve as buffers for the data consumers that use that data. Whenever new data is generated, a data distribution task (34) initially stores the data in the associated source file and, then based on the contents of the sink link table, copies the data into the appropriate sink files associated with the data consumers that use the data.