Patents by Inventor Aurelie MATHIEU

Aurelie MATHIEU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHAGE-DERIVED PARTICLES FOR IN SITU DELIVERY OF DNA PAYLOAD INTO C. ACNES POPULATION
    Publication number: 20260109991
    Abstract: The invention relates to C. acnes carrying DNA vectors with a C. acnes phage packaging signal and a gene of interest. The invention encompasses a C. acnes producer cell carrying DNA vectors, with a C. acnes phage packaging signal and a gene of interest, for the production of phage-derived particles that can robustly transduce C. acnes receiver cell allowing transgene expression. The invention encompasses C. acnes phage-derived particles carrying these vectors, C. acnes containing these vectors or modified by transduction of these phage-derived particles, and methods of using these phage-derived particles.
    Type: Application
    Filed: October 24, 2025
    Publication date: April 23, 2026
    Applicant: Eligo Bioscience
    Inventors: Aymeric LEVEAU, Ines CANADAS BLASCO, Aurelie MATHIEU, Antoine DECRULLE
  • PRODUCTION OF LYTIC PHAGES
    Publication number: 20240247238
    Abstract: The present invention concerns a production bacterial cell for producing lytic phage particles or lytic phage-derived delivery vehicles, said production bacterial cell stably comprising at least one phage structural genes and at least one phage DNA packaging genes, said phage structural gene(s) and phage DNA packaging gene(s) being derived from a lytic bacteriophage, wherein the expression of at least one of said phage structural genes and/or at least one of said phage DNA packaging gene(s) in said production bacterial cell is controlled by an induction mechanism.
    Type: Application
    Filed: February 28, 2024
    Publication date: July 25, 2024
    Applicant: Eligo Bioscience
    Inventors: Jesus FERNANDEZ RODRIGUEZ, Antoine DECRULLE, Aymeric LEVEAU, Ines CANADAS BLASCO, Aurelie MATHIEU, Thibault CARLIER
  • Production of lytic phages
    Patent number: 11952595
    Abstract: The present invention concerns a production bacterial cell for producing lytic phage particles or lytic phage-derived delivery vehicles, said production bacterial cell stably comprising at least one phage structural genes and at least one phage DNA packaging genes, said phage structural gene(s) and phage DNA packaging gene(s) being derived from a lytic bacteriophage, wherein the expression of at least one of said phage structural genes and/or at least one of said phage DNA packaging gene(s) in said production bacterial cell is controlled by an induction mechanism.
    Type: Grant
    Filed: July 7, 2023
    Date of Patent: April 9, 2024
    Assignee: Eligo Bioscience
    Inventors: Jesus Fernandez Rodriguez, Antoine Decrulle, Aymeric Leveau, Ines Canadas Blasco, Aurelie Mathieu, Thibault Carlier
  • PRODUCTION OF LYTIC PHAGES
    Publication number: 20240010994
    Abstract: The present invention concerns a production bacterial cell for producing lytic phage particles or lytic phage-derived delivery vehicles, said production bacterial cell stably comprising at least one phage structural genes and at least one phage DNA packaging genes, said phage structural gene(s) and phage DNA packaging gene(s) being derived from a lytic bacteriophage, wherein the expression of at least one of said phage structural genes and/or at least one of said phage DNA packaging gene(s) in said production bacterial cell is controlled by an induction mechanism.
    Type: Application
    Filed: July 7, 2023
    Publication date: January 11, 2024
    Inventors: Jesus FERNANDEZ RODRIGUEZ, Antoine DECRULLE, Aymeric LEVEAU, Ines CANADAS BLASCO, Aurelie MATHIEU, Thibault CARLIER